Since you asked for the "most serious" complications of chin liposuction, although I have never heard of it, the top of the list would be dying. Liposuction is real surgery and should not be undertaken in an unhealthy patient or be done by an unqualified physician in an unaccreditied facility. The second would be an infection or hematoma. The final would be having contour problems or poor skin shrinkage which is more common when the patient was not a great cnadidate in the first place. I am very strict about who is a good candidate for chin liposuction because they must have great skin for a great result. If the skin is loose, then you need a necklift or a facelift.