Will a Colon Cleanse Effect the Lasting Results of Botox?

A colon cleanse should not affect the performance of Botox.

Botox molecules target sites on nerve fibers that release a chemical transmitter called acetylcholine.

Acetylcholine causes muscles to contract when the chemical transmitter binds to receptors on the muscles.

Essentially, Botox works on nerve fibers. And a colon cleanse should not interfere with this process

The aesthetic effect of Botox  is local, within the injected facial muscles. A colon cleanse will not disrupt or otherwise affect your aesthetic results from Botox.

That is an unusual quesiton. I can see where you may be led to believe that a colon cleanse will purify the toxins from your body but I doubt that it will eliminate the botox or diminish its effects.