It's great that you're being mindful of combining different products in your routine. Using a 0.025% Retin-A gel (prescribed) alongside a glutathione serum can be a beneficial addition to your skincare regimen, but there are a few important considerations to keep in mind to ensure you're getting the best results while minimizing any potential irritation. Since Retin-A (tretinoin) can be potent and might cause some initial irritation, it's a good idea to start slowly. Begin by using it only a few times a week and gradually increase frequency as your skin becomes accustomed to it. This will reduce the chances of experiencing excessive dryness or redness when combining it with other products. It's often recommended to use Retin-A in the evening, as sunlight can degrade its effectiveness. If you're planning to incorporate a glutathione serum, consider using it in the morning routine to avoid any potential interactions with the Retin-A. Before introducing any new products into your routine, especially if you're using a prescription like Retin-A, it's a good idea to consult with a dermatologist or skincare professional. They can provide personalized guidance based on your skin type, concerns, and the specific products you're using. Whenever you're combining new products, it's a good practice to perform a patch test on a small area of skin to ensure you don't have any adverse reactions. Both Retin-A and glutathione can potentially increase skin sensitivity to the sun. Using a good quality sunscreen during the day is crucial to protect your skin from UV rays. Also, keeping your skin well-hydrated with a suitable moisturizer can help mitigate any dryness that might result from using Retin-A. As you start using both products together, pay attention to how your skin responds. If you notice any excessive dryness, redness, or irritation, it might be a sign to adjust your routine or usage frequency. Remember, everyone's skin is different, and what works for one person might not work the same way for another. Taking a cautious and gradual approach to integrating new products into your routine is key to achieving the best results while maintaining the health and balance of your skin.