Chronic Fatique and Botox. Side Effects of Botox?

Chronic fatigue patients can certainly have Botox. The side effects you are describing occur in about 1-2 % of patients. Will you be one of this tiny minority? No one can predict that for you. If you experience this side effect generally then you may decide to avoid treatment in the future.

There is still a lot of work that needs to be done to understand both, chronic fatigue syndrome and it's cause(s) as well as the potential systemic side effects that may occur, but are very rare, with Botox.

I have treated patients with Botox injections for 20 years and have had only two patients that I can remember telling me they felt some flu like symptoms for a couple of days after the injection and they both returned for more Botox when it wore off several months later and did not experience the side effect again.

I am not aware that there is any cause and effect of an exacerbation of the chronic fatigue syndrome after botulinum toxin treatment.

None of my patients have experienced these symptoms in the past. However, we understand very little about chronic fatigue syndrome. Thus, it's very hard to make a prediction for you. If you can tolerate the symptoms you experience with a flu shot then it might be worth trying. If it's a truly miserable experience to get a flu shot you might have the same experience with Botox and it might not be worth the risk. I hope this information is helpful.Stephen Weber MD, FACSWeber Facial Plastic Surgery