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Does Spironolactone cause vaginal dryness?

March 16, 2019
Asked By:nnikki625 in California, CA

I am a 37 year old woman who has struggled with hormonal acne for the last 3 years. My dermatologist prescribed 50 mg of Spiralactone. I was on Spiralactone for 4 months when I began experiencing vaginal dryness. I also experienced late and light periods (I’m on the pill and have never experienced this). Is it possible Spiralactone is causing this issue?

Answers (1)

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September 18, 2020

Answer: Spironolactone side effects

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Laura A. Katz, MDBoard Certified OB-GYN
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MOST RECENT
September 18, 2020

Answer: Spironolactone side effects

2 people found this helpful
Laura A. Katz, MDBoard Certified OB-GYN
(12)
Visit Profile

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Spironolactone side effects: do you suggest that I tough it out, adjust the dose, or discontinue taking it?
Amy Y. Paul, DO, FAAD says:

Thanks for your question.  You might want to ask your dermatologist or prescriber if decreasing the dose is an option.   Some of my patients do fine on just 25mg daily without side effects, but found the 50mg too much.  If you decide the sprionolactone is absolutely not...

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Should you split your dose of spironolactone for best results?
Reuel Aspacio, MD, FAAD - Account Suspended says:

Hello and thank you for your question. In general, I recommend my patients to take the medication once a day at night. However, depending on the side effects experienced, the dosing and frequency may vary. I would recommend consulting your board certified dermatologist for evaluation of your...

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How long will spironolactone stay in my system once ceased?
Laura A. Katz, MD says:

Spironolactone has a half life of about 16 hours for the active metabolites of the drug.  This means that it would take about 36 hours before traces of spironolactone should not be detected in your blood.  Hope this helps.

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