I have been using Botox, and have had Xeon recommended instead. What is the difference?

Question

Can you please give me some info on this product Xeon? I've had Botox first time 7 wks ago and i was advice by my nurse that my next injection age thinks I would really like Xeon. But as it's a different product I want to get some info on it first please

Matthew Richardson, MD · Answer

Botox and Xeomin are essentially the same thing.  They are both neuromodulators.  Like Botox, Xeomin is commonly used for cosmetic purposes to treat wrinkles and fine lines of the forehead, glabella (between the eyebrows), lateral orbital areas (crow’s feet), and lateral nasal areas (bunny lines). In select patients, Xeomin can also be used to improve down-turned corners of the mouth, vertical banding of muscles in the neck, and wrinkling of the lower eyelids and chin areas. 
I would recommend having a consultation with an expert physician injector to determine what your goals are and to discuss both products further.
All the best,

J. Jason Wendel, MD, FACS · Answer

Thank you for your question in regards to Xeomin. Botox and Xeomin are just two different brands of botulinum toxin molecule. They are prepared and stored differently, but have the same results. To be sure, see two or more board-certified providers in your area for a complete evaluation to make sure you are a good candidate and that it is safe for you to have treatment. I hope this helps.

Larry S. Nichter, MD, MS, FACS · Answer

Xeomin, Dysport and Botox are all preparations of botulinum toxin A derived protein that works at the nerve-muscle interface to relax targeted muscles. Each preparation is slightly different, for example the protein size differs. Dysport and Xeomin have been around in Europe for a long time and more recently introduced in the USA. Note the dosage is not the same between the drugs though each works well in my experience.

George Yang, MD · Answer

Hi Clairearcher,If you did not know whether you had Xeomin injections or Botox injections, most likely you would not be able to tell the difference.  The Botox molecule is larger (900 kD kilodalton) and has some proteins that accompany the actual active portion (150 kD) which causes the muscle to be paralyzed.  The Xeomin molecule has only the 150 kD active Botox molecule without the accessory proteins that Botox cosmetic has.Since the active portion of the molecule is the same, it should work same.  Both Botox and Xeomin come in 100 unit vials and the dosing for Xeomin is the same as Botox, so I don't need to make a special calculation as I need to do with Dysport (2.5 ratio.)Currently the Xeomin vials are less expensive during their introductory roll out, but this may change in the future as with Dysport which started off cheaper, and is now about the same price as Botox cosmetic per vial.Best,Dr. YangP.S. There is a new feature on Realself, which is the "Follow" button. It is similar to the "Like" button on Facebook. If you like my response or any of the doctor responses while you research on Realself, you should "Follow" them. You will get email updates, when the doctors you follow post any new answers to questions, post new photos, or have any new reviews.

Young R. Cho, MD, PhD · Answer

The three brands of neurotoxin that are on the market are all effective.  We offer all three at our practice.  How we do it at our business depends on several factors.  Brand preference is definitely a consideration.  Some patients request only one brand because their prior experience.  I would say they all work pretty well.  You do have to be very careful about the price per unit as each brand requires a different amount to get similar results. In addition, I would say the most important aspect of the result is the qualifications of the injector and their experience.  I have had many patients who follow price as their main determining factor and then come to me afterwards because they had purchased the same number of units in the past from me, but were not happy with their service when they went somewhere else based on price.There is a certain skill required to use these products to help address your aesthetic concerns.

Lisa Gardner, DO · Answer

I use Xeomin almost exclusively in my practice, and my patients love it. They are essentially different brands of botulinum toxin, but for all intents and purposes they work the same. My patients report seeing the effects of Xeomin a full day or two sooner than Botox.

Bruce E. Katz, MD · Answer

Thank you for your question. Botox and Xeomin are neuromodulators that help with muscle control and smoothing fine lines and wrinkles. They are essentially different brands of botulinum toxin. For more information, I recommend getting a consult from a board-certified dermatologist.

Kristin J. Tarbet, MD, FACS · Answer

They are essentially the same with the same mechanism of actions and result. They are stored differently, but that is about the only difference.

Navin K. Singh, MD · Answer

Botox has been around for longer and is therefore well known. The results are similar yet doses will vary between the two products. Botox can be harder on patients who are sensitive to the pain. The full results of either treatment will start to show 5-7 days after treatment. If you are unhappy with the results of botox you may want to discuss the option of using Xeomin as it is an alternative.

Michael H. Gold, MD · Answer

Thanks for your question and the easiest answer is that Botox and Xeomin are very similar in their effects and what they do, how long they last, and what they are all about. There are differences – we call Xeomin a pure toxin, as it does not have the same proteins around the molecule that we see in Botox. What the need for these proteins is not known and many of the newer toxins are pure and do not have them. Most of the medical literature shows that the two are interchangeable – they are mixed the same, they work the same, and they last the same.  Some in the Botox family think that it takes more Xeomin to make it work, and that it lasts longer than Xeomin – but most of the studies suggest equivalence.What is important that skilled injectors in the offices of board give them all certified dermatologists or plastic surgeons as they understand toxins the best and know that anatomy and the best places for the injections to take place for the most optimal results.

I have been using Botox, and have had Xeon recommended instead. What is the difference?

Answers (16)

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