Botox Stopped Working: Resistance?

December 9, 2008
Asked By:DABFS in Jupiter, FL

I've had Botox for frown lines, crows feet, and forehead wrinkles about 6 - 8 times since 2004. I travel a lot so have been to several different doctors and always had wonderful and almost immediate results. In January this year, I went to a new doctor and was disappointed with the results - I felt the treatment was too conservative - did not get as dramatic or long lasting result. In October, I went to someone else, absolutely no results; 2 weeks later they did more Botox - still no results. Then about a week ago, after consulting with the Botox rep, they tried to inject other facial muscles - still no results. I have been reading about Botox resistance, and it seems patients with resistance experience this from the very first injections. But mine is years after the fact. What does this mean? What can I do short of surgery?

Answers (7)

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December 10, 2008

Answer: Resistance not always immediate

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Richard Baxter, MDBoard Certified Plastic Surgeon
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VOTED MOST HELPFUL
December 10, 2008

Answer: Resistance not always immediate

2 people found this helpful
Richard Baxter, MDBoard Certified Plastic Surgeon
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December 21, 2023

Answer: Resistance to Botox

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Larry S. Nichter, MD, MS, FACSBoard Certified Plastic Surgeon
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MOST RECENT
December 21, 2023

Answer: Resistance to Botox

1 person found this helpful
Larry S. Nichter, MD, MS, FACSBoard Certified Plastic Surgeon
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December 18, 2009

Answer: Botox resistance is possible

1 person found this helpful
Harold J. Kaplan, MDBoard Certified Facial Plastic Surgeon
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December 18, 2009

Answer: Botox resistance is possible

1 person found this helpful
Harold J. Kaplan, MDBoard Certified Facial Plastic Surgeon
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December 10, 2008

Answer: Filler versus paralytic

David C. Pearson, MDBoard Certified Facial Plastic Surgeon
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December 10, 2008

Answer: Filler versus paralytic

David C. Pearson, MDBoard Certified Facial Plastic Surgeon
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February 17, 2009

Answer: Botox Resistance

February 17, 2009

Answer: Botox Resistance