Primary biliary cirrhosis is not a contraindication to botox or fillers, however, primary biliary cirrhosis can result in some conditions which may be contraindications.
Because PBC is a scarring condition of the liver, which manufacturs many of the clotting factors, a person with PBC may be more at risk of bleeding from cosmetic procedures.
Also, there is a certain amount of immune system compromise in PBC making a patient with this condition more predisposed to infections.
So, it depends on where you are with this disease. If there are no abnormalities with bleeding or infection, then there is no contraindication for injectables. I recommend a consultation with a board-certified dermatologist or plastic surgeon and a discussion of the risks and benefits of these procedures for you.
Also, Botox and fillers are injected, processed and dissolved locally in the skin. They generally don't enter the body, so they should not affect your condition.