I'm afraid there is not enough information to answer your question precisely. If you mean that you just had it done, today and the ink marks remain and you're not sure how to remove them, you should wait four hours after the Botox and then rub gently with rubbing alcohol and a Qtip. There are different inks that doctors use on the skin and for the reason you mention, ink for botox, if used, should not be as durable as surgical marking pens. If however, you mean that you had botox done days ago and still have the ink, then it is possible that the ink is either very durable and will fade with each washing and exfoliation or it even could be a slight tattoo if the needle trapped ink in the dermis. Please see your doctor to help you eliminate the source of your dismay.