Can Botox Eventually Cause Muscles to Atrophy Enough that Botox is no Longer Necessary?

Botox will only temporarily paralyze and relax the muscles and can typically last 3-4 months on most patients. Overtime with use of Botox the muscles will relax but this means less wrinkles. As you mentioned, with changed habits and not frowning as often, this CAN lead to not requiring Botox as often or at all

Botox is injected directly into a muscle to weaken it. Repeated injections can cause the muscle to atrophy, but it will not cause the muscle to become permanently still. If a patient if off Botox long enough, all function of the muscle will return.That being said, patient tend to use less Botox overtime and need injections less frequently. It patients are able to "re-train" their muscles that is an added benefit. I do not think the muscle re-training is secondary to the effect of Botox.

After continued use of Botox in patients, they typically are able to cut back on the amount and frequency of injections.That being said, Botox is temporary and is not a permanent solution.