In November I had my first injection. I went to a local board certified plastic surgeon with a good history. wanting Juvederm injected into my upper lip to try to correct an asymmetry. The doctor injected a full syringe into my upper lip. After 3 days developed two large lumps formed. After a small poke and drain, the lumps went down. After 2 weeks the effect of Juvederm had disappeared completely. Is it possible my body rejected the substance and metabolized it too quickly?