Im 22 male and experiencing severe hair loss in crown area and middle of the scalp..can I use mindoxil?

Before starting on medication for hair loss treatment, it is a good idea to see a doctor for an examination.  You should have a diagnosis before starting treatment.

In my opinion, you need to be evaluated by a hair specialist. You will need blood work, an excellent history and probably a biopsy. It is still possible for you to have  genetic hair loss. However, I am concerned that your hair loss may be related to the isotretinoin treatment. It is common for people on isotretinoin to lose hair. A telogen effluvium of another ideology needs to be investigated . Should this work up be essentially negative, then minoxidil and finasteride would be a good start. Micro needle rolling, low level laser and platelet rich plasma  have been  helpful in early hair loss. Hope this helps. Good luck.

Minoxidil is certainly reasonable to try, but you should see a doctor specializing in hair right away.  If you have pattern baldness developing, this is a problem that will likely get worse over time unless aggressively treated. If you have another reason for your hair loss it could be due to a medical condition that will need diagnosing. 

I'd advise you see a physician who specializes in hair loss. See a few to get a broad approach. Most likely you have genetic hair loss.  A full history is needed. Most men do not need blood tests and most men do not need a biopsy. Isotretinoin is not a common cause of hair loss (less than 3 % of users). If you have genetic hair loss you can discuss with your physicianminoxidil 5 % - twice dailyfinasteride 1 mglow level laserplatelet rich plasma