Are Large Blisters Common After Laser Therapy?

The legs heal very slowly.  That is a long time to be healing, though.  If you had a ruby laser, I would expect a week or so of your legs looking bad.  But for most lasers, you should be healed. I would have to know your  laser and therapy for an accurate answer.  I would also not rule out that you are having a reaction to the Neosporin and inflamed from the medication.  I would switch to Aquaphor.  Be sure to talk with your doctor about this first.

If appropriate precaution is taken (e.g. perform test area, icing if chilled tip not availabl) , there should not be any blistering or scabbing after laser hair removal. When blistering or scabbing occurs, you should demand to be evaluated  by the supervising physician, start lubricating the open sores and possibly start oral antibiotics to prevent secondary infection. This is illustrative of the need to ascertain the supervising physician of a laser clinic be a board-certified dermatologist or plastic surgeon who is competent to manage post laser complications such as blistering and/or post-treatment pigmentation.

A CO2 laser creates a second degree burn of the face and creates an open wound or blister. The healing process will lead in selected patients to an aesthetically improved appearance. There are negative consequences as well.