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Please ask your doctor who is prescribing you Accutane. They would be able to better answer this question.
Your own dermatologist is the best person to guide you in using any skin product while on Accutane. All your skin will be much drier than normal, so there's a potential that you'll have some unusual irritation from Latisse that you'd not experience otherwise. I'm going to bounce you back to your treating doctor as he or she is the final authority when you are using medication that has substantial effect on your skin.
I have never heard of any problems in patients using Latisse while on Accutane so this should be perfectly safe. If you still have any concerns you should check with your physician who is prescribing your Accutane.
If you are experiencing any eyeball changes, I would discontinue the product and seek the exam of an ophthalmologist.
Latisse extends the growth phase of eyelashes, but intrinsic characteristics of the eyelashes will not change like curliness.
Hi there- Check with the surgeon who performed your PRK, but in general, and as long as you follow the instructions, there should be no reason that you cannot safely and effectively use Latisse.