Hi, I understand your concern—wanting to protect and maximize the results of your Radiesse is completely reasonable. Minoxidil primarily works on hair follicles and does have some effects on collagen production in the skin, but there’s no evidence that it negatively impacts Radiesse, which is a calcium hydroxylapatite filler that stimulates collagen in the deeper dermis. Using minoxidil on the jaw area wouldn’t reduce or interfere with the volume of your Radiesse. As for collagen supplements or powders, while they may support your overall skin health, they do not directly increase the volume of Radiesse. The filler itself creates structure and stimulates collagen locally, which is separate from what oral supplements provide. That said, maintaining good skin health with proper hydration, nutrition, and sun protection can help your results last longer and look smoother over time. Minoxidil won’t harm your Radiesse, and collagen supplements are supportive but won’t boost filler volume.