A Préime DermaFacial combines five technologies in one comprehensive treatment that can deeply cleanse, exfoliate, hydrate, tighten, and rejuvenate skin on the face, neck, and décolletage.
Dr. Anil Rajani, a physician in Portland, Oregon who specializes in aesthetics, was an early adopter of Préime. He says he's "been consistently impressed by how this system elevates medical facials to a new level" with "five powerful technologies—each targeting different layers of the skin—to cleanse, hydrate, tone, and firm while enhancing the delivery of active ingredients deep into tissue. The result? Smoother, brighter, more hydrated skin with that coveted ‘glass skin’ glow."
According to Dr. Rajani, it's not just the technology that sets Préime DermaFacial apart: it gives providers "the ability to customize treatments and prepare the skin for more advanced procedures." In fact, providers often recommend pairing a Préime DermaFacial with complementary treatments like laser resurfacing, polynucleotides, and exosomes, for an even more dramatic improvement in skin quality. "With tools like VibroX and CO₂ microbubbles driving oxygenation and absorption, we’re finally solving the long-standing challenge of effective ingredient penetration," explains Dr. Rajani. In his practice, this has been "a game-changer in results."
Each facial treatment involves a series of steps.
Here's what to expect.
You’ll see an improvement immediately afterward, but the best results come after a series of 3 or more treatments, spaced every 4 to 6 weeks. Some practices also recommend ongoing maintenance treatments to keep your skin looking smooth, firm, and vibrant.
“Préime DermaFacial is one of my go-to treatments for achieving that healthy, dewy glow patients love, without any post-treatment redness or downtime," says Dr. Ashley Magovern, a board-certified dermatologic surgeon in Manhattan Beach, California. "Its five-in-one technology allows us to treat all layers of the skin in a single session, from deep hydration and exfoliation to skin tightening and enhanced ingredient absorption." Like Dr. Rajani, she also appreciates its customization options, which are "ideal for tailoring to each patient’s unique skin needs while delivering visible, radiant results.”
Gabby Garritano, founder of JECT medspas in NYC, is also a fan. She says Préime DermaFacial "complements our minimally invasive, holistic approach—allowing clients to seamlessly incorporate advanced skincare into their routines while achieving visible, lasting results." She praises it for "offering a versatile, results-driven treatment."
Pros
Cons
Most patients don’t experience side effects after a Préime DermaFacial, but it is possible to experience mild inflammation or swelling in the few hours post-treatment. People with sensitive skin might be more irritated than others, so if that’s a concern for you, talk with your provider about how to avoid it.
To help reduce the chance of side effects, avoid these things for at least 48 hours afterward:
Updated May 19, 2025