Why do you get hyperpigmentation of the skin following sclerotherapy?
Although several reasons are responsible for hyperpigmentation of the skin after sclerotherapy, namely a postinflammatory condition or hemosiderin deposition, the propensity of published studies point to the fact that it is the hemosiderin deposition as seen on histologic studies that are responsible for the pigmentation. The staining of hemosiderin is in the dermis and is independent of the type of sclerosing solution used.
The skin has three layers, epidermis, dermis and subcutaneous tissue. The middle layer is the dermis. It contains blood vessels, nerves, hair roots and sweat glands.
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Hratch L Karamanoukian, Md