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POSTED UNDER Restylane REVIEWS

My Story - New York, NY

ORIGINAL POST

Ten years ago I had a consultation with plastic...

New York5025
$800
Ten years ago I had a consultation with plastic surgeon for a procedure. While determining if the procedure was a good choice the doctor suggested that I get a filler called Restylane for under my eyes. He said it would help my tired look and fill in the hollow circles under my eyes. While I didn’t go to him for this issue I did agree that it may be a good idea. He said it was safe and would benefit me. I had just turned 40 and thought this would hold back the hands of time.

That is when I started with these injections. I did go to a few different dermatologists and plastic surgeons throughout the years and never had an issue. I tried Juvederm, but I didn’t like the effects, it caused a blue hue under my eyes.

Two years ago a friend of mine recommended a dermatologist that she was going to who is board certified and had performed 1,000’s of injections. He dissolved the Juvederm immediately and said it wasn’t injected properly which is why I had this blue hue and a bag was forming under my eye.

He waited two months before he injected me with Restylane. Before I had gone to him I had extensive dental work which also caused me some sinus issues.

A few months after the injection I noticed some red swelling under one eye. I called my dermatologist and informed him of this issue. He said that I probably was allergic to some topical eye cream I was using. He said if it was the Restylane, I would have had the reaction immediately. He told me he needed to see the swelling to determine what it was. The swelling only lasted for a day or two and happened so infrequently that by the time I made the appointment the swelling was gone. So I started taking pictures. I showed the picture to my dermatologist and again he said it was from topical creams, so I threw out all of my expensive anti-aging eye creams, face creams, etc. I started using cetaphil cream.

July of 2013 I had my yearly injection of Restylane. At the end of August I noticed some swelling for a day or two. Then over the course of the next few weeks the swelling started every week and would last for three days. By October the swelling became severe. I went to see my primary care doctor finally a doctor witness the actually swelling. She gave me antibiotics and said I had a skin infection and it should be cleared up in a week. Two weeks after the first antibiotics the swelling came back under both eyes and cheeks. I immediately went back to my primary care physician. At this appointment she didn’t think it was a skin infection, but either an allergy or a sinus related issue. I made an appointment with an allergist who took a series of blood tests and a sinus scope. He said I had a low grade sinus infection, but thought this issue was from my immune system. All of my tests came back negative. I informed both doctors that I was injected with Restylane and they both said that it definitely wasn’t caused by Restylane, that I would have gotten this reaction immediately.

I started researching this on the internet and found other people with the same exact issue as me. I also work for a medical education company who teaches physician’s how to inject these products. After speaking with my boss she told me this reaction could be caused by a biofilm infection and could have spread from the dental work I had done. There was a faculty meeting just a month prior discussing this topic.

I truly believe that it’s not the fault of the injector or the product, but the fact that I may have already had some sort of infection. Once I was injected it may have disturbed the infection which attached to the Restylane.

I went back to my dermatologist with this information. He had never seen a case like this before and was shocked when he saw the pictures and then saw my swelling first hand. He dissolved the Restylane and immediately put me on 500 milligrams of Biaxan twice a day for 5 weeks. For three weeks I didn’t get any flare ups, but became very sick from the antibiotic. I was just approaching my last week of the antibiotics when the swelling returned and it was severe. I got violently ill from the antibiotics and couldn’t hold down any food. I went back to the doctor this past Tuesday and he reinjected me with the solution to dissolve any remaining Restylane. He put me on a new antibiotic for 30 – 60 days depending on how I can handle it.

It’s been two weeks since the Restylane was dissolved for the second time and I have been fine until today, January 22. I missed one antibiotic and already see swelling under my eye. I have another two weeks of antibiotic so hopefully this will help. I will keep you updated.

Replies (20)

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January 25, 2014
New York, has your doctor told you that you have a biofilm infection? I had one caused by Restylane to the tear trough area. You can read my story here: http://www.realself.com/review/new-york-ny-disastrous-result-injecting-restylane-tear-troughs . I finally had eyelid surgery yesterday, and the surgeon, who is an expert in biofilm infections, told me there was still some remaining encapsulated Restylane, present after 15 months and after dissolving with hyaluronidase. Be sure to be persistent and get the proper treatment until your infection is cleared! Sadly the whole ordeal left my undereyes a mess, which is why I finally elected to have the surgery.
January 30, 2014
Hi Sallify, Yes, I definitely have a biofilm infection. My doctor is trying so hard to help me, but I am still in bad shape. I have to go back on the original antibiotic once I'm finished with the current one. My eye and cheek swelled up so bad again last night, I don't know what else to do. He is going to dissolve it for a third time next week once the swelling goes down. Who is the doctor that is an expert in biofilm? I can't seem to find anyone who really understands this. Thank you Rose
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January 30, 2014
I am so sorry to hear what you're going through, Rose. I went through a similar hell for about six months, then was left with saggy, baggy uneven eyes. Rhoda Narins in New York is an expert in biofilm infections and their treatment. And the plastic surgeon who just removed the last of the encapsulated Restylane for me last week in L.A. is Dr. Kami Parsa. Here is a link to an article that Dr. Narins wrote on treating biofilms from fillers: http://dermatologytimes.modernmedicine.com/dermatology-times/news/modernmedicine/modern-medicine-feature-articles/biofilms-dermal-fillers-manag I haven't yet reported my infection to Medicis, the manufacturer of Restylane, but reading more and more stories here of women here who are having biofilm infections--diagnosed and undiagnosed--makes me think that all patients suffering these symptoms should report these symptoms/infections to the maker.
January 30, 2014
So....from the research you've both done Sallify and NY is this infection something that you already HAD somewhere in the body that attaches to the artificial filler (could be Resty, Sculptra etc) and because of the properties of the filler becomes hard for the antibiotic to attack....OR is it that there has been bacteria introduced through a less-than-clean injection needle or injection site? Or do they think that the source of the infection is of less importance than the fact that the filler provides a host environment that makes it amost antibiotic immune.... btw...you too are providing a real resource to the RS site. thanks, grace60
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January 31, 2014
From my understanding, the bacteria can be introduced either way, internally or externally. I've learned through this that prepping the skin before injecting filler needs to be as precautious as before surgery, swapping the skin with Betadine. One's skin should be clean and make up free before injecting, not just quickly swiped out with an alcohol wipe. Otherwise bacteria can be introduced when injecting the filler. The way biofilms operate is the bacteria "encapsulate" the filler, creating a protective shell around the filler in which the bacteria can multiply and hang out. This shell that they form then protects the body's immune defenses or antibiotics from getting to the bacteria and killing it, which is why it is such a very difficult infection to get rid of. The plastic surgeon who just removed the last of my filler said that it's almost impossible to pinpoint and target all of the filler and get rid of it all just through hyaluronidase injections alone. The sad news is that in some (most?) cases it may be necessary to remove any remaining filler surgically. My PS said that this information is new, new, new. Most doctors are still unfamiliar with the risk of biofilm infection from fillers and don't have the first idea how to treat it. I am making it my mission to get the word out. I think there's an newspaper or magazine article here that needs to happen.
January 31, 2014
Too bad Oprah isn't still on but how bout Dr Oz. I think this is really a great thing you are doing. Fillers are a big business and it will be a while before this message gets out if it is the plastic surgery, medispa or dermatological community who must sound the alarm. They are making a lot of money from this maintenance product. And the scary thing is that hyper-clean skin surface is not enough. Apparently any minor infection from dental work or sinus infections can easily migrate to anywhere the filler has been placed in the mid face. I hope you can get this information out and widely circulated. If the filler manufacturers and the practitioners who use it know biofilm to be a problem they really have a duty here. Up to this point when a woman presented with rashes they were told it was an immune reaction and made to feel like their bodies were attacking some harmless injectable. Usually they were prescribed a steroid to tamp down the reaction or an antibiotic which, as you pointed out, is unable to penetrate the encapsulation. Thanks for what you have done so far. You identified something that was certainly wrong with your outcome and you persisited to find out your truth even when the PS was offering you no solution. What a refreshing thing....to see clearly when something has gone wrong and let others know there's a problem In this case...a big one. grace60
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February 14, 2014
SO SORRY. Hope you feel better soon. I am glad we have RealSelf to come to to give our experiences. We never hear of all these problems we experience with cosmetic procedures. Thanks for sharing your experience.
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February 14, 2014
I agree. I hope all these cases are being reported. I have had my problems with fillers and people need to know of adverse problems prior to having the fillers. Thanks
March 27, 2014
what is biofilm?
March 27, 2014
I agree Grace n and thank you for posing those questions so well. thta was exactly what I wanted to now.
April 30, 2014
I had restylane injected under my eyes in March of 2008. Immediately, my tear troughs filled with blood and such severe bruising, that as I began my 1 block walk to my car, several people turned and actually GASPED at what they were seeing. A couple hours later, my eyes were burning so bad and head hurting, that I feared for my vision. I could hardly see through the burning and swelling. As I pulled into a service station to gas up, my vision was so off that I hit one of the pumps. Ageless/Schell in Seattle insurance company called me regarding the problems after several months of suffering and I was so sick I couldn't even follow through with the claim. SIX YEARS later and I still have large olive sized bags under each tear trough that constantly swell and recede. I cannot wear sunglasses or glasses, because when I do even for 10 minutes they leave heavy 1/8 inch impressions in the swollen tissue! Hyalauronase does not fix the problem, it only makes it lumpier! I am in good shape, had a lower blepharoplasty done several years before the Restylane ruined my undereyes, and ever since the injections, my tear troughs have been double the size of what they were before my bleph which was done very well. I have developed 8 brain lesions, the most recent on my brain stem, and suffer from strange pattern headaches. Can anyone offer me any medical or legal advice? I have a child to care for and am all he has!
December 10, 2014
Thank you for sharing.
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February 21, 2015
thanks for sharing!
February 26, 2015
oh no!! what a nightmare - i have been through the same thing for the last 2 years -- it doesn't matter whether i take anitbiotics or not - these biofilm infections are highly resistent to antibiotics - google as much as u can about biofilm and injectibles - it is such and incredible shame that even the most sought after and famous dermatologist have not read about these problems because they are becoming more and more common and there are dr conferences about just these kind of problems! i am almost 2 years into my biofilm mess from restylane injections and i have found that when i am tired or run down or have pushed myself and my immune system that the swelling will reoccurr -- unfortunately, even dissolving the restylane doesn't work and i have read that you can spread the infection with the dissolver -- i have now opted to just wait it out until the restylane dissolves on its own - and will never ever but another filler in my face again!
February 26, 2015
On another review just yesterday I was told by a self appointed expert that biofilm could be dissolved with an injection. You should check out her post because it could solve all your problems. She has posted under the ID of Kellyspi . She seemed very sure of herself so maybe she could direct you to the physician she knows who can help you out with a simple injection.
November 8, 2015
I am having the same problem with restylane under eyes since august. The Dr. gave me Cadista and it makes the humps and redness go away but it comes I AM GOING TO GO TO another Dr. I was told there was nothing to dissolve Restylane
UPDATED FROM New York5025
6 months post

Still Swelling Up

New York5025
So I have been on four antibiotics and nothing is working. I have had the restylane dissolved twice. I saw my doctor January 28 and he suggested that I go back on the original antibiotic which made me sick, but I really don't have a choice. I have been swelling up everyday now. I have an appointment next week to try and dissolve any remaining product next week if I am not swollen. I have been on antibiotics for three months now, which I am very concerned about since this will cause stomach issues. I am posting a pictures of the swelling when this started. I have some new pic from this week that I will upload later this week.

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UPDATED FROM New York5025
7 months post

Getting Better

New York5025
Well it's been some time since my last update. I have had the product dissolved three times now and went back on the Biaxin antibiotic. It's now been over four months on antibiotics. So far I'm good. I haven't swelled up since February 2nd. I have five more days on the antibiotics, once I'm done, hopefully I won't swell up again.

Replies (2)

March 13, 2014
Hi, I am so very sorry to hear about your experience!! Thank you for publishing and getting more info out to all of us. You are a very beautiful lady. Hopefully this last round of antibiotics will do the trick for you. (Hope you are taking VERY HIGH doses of Probiotics!) I want to throw something out to you that may or may not have any affect on your swelling. I have had health issues in the past, and I now deal with swelling under my eyes into my cheek area. It is a mystery to my primary care physician as well as my dermatologist. I had Restylane injections to try to help my under eye circus. The injections did help me for my good days, but I still continue to have bad days. I have since learned (through trial/error) that eating sugar will absolutely guarantee a blow up under my eyes. I cannot eat any desserts or God-forbid, chocolate. I can tolerate a small piece of cake/muffin/cookie from time to time, but anything that is high is sugar, Forget It! Keep me posted on your progress. Positive thoughts coming your way!!
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April 27, 2014
You are so right on it! Sugar and high starchy carbs are highly inflammatory. The other possibility is that she may have an autoimmune reaction to gluten. According to Dr. Perlmutter, people are allergic to gluten and don't even realize it. If people have any type of autoimmune condition, ADD, ADHD, Schizophrenia, depression, MS...he recommends getting a few tests, one specifically to test gluten sensitivity. He lists the tests in his book Grain Brain. I was diagnosed with Hashimotto Thyroditis as a condition of the body rejecting the thyroid gland. My endocrinologist told me that I would to be on thyroid medications for the rest of my life. Fortunately, I found a blog and people with the very same condition and had it revered once they got off of gluten. I gave it a try, stopped taking my thyroid meds and haven't felt better since. My tests have come back normal but the doctor didn't think it was related to the gluten, she thought that titers could switch on and off. It's been five years and I am doing perfectly as I am gluten and grain free. I hope this post doesn't sound like a ridiculous tangent. It would be worth a try and if it works please do tell us about it.