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What Are Potential Latisse Side Effects?

Can Latisse cause any side effects I should be aware of?  If so, what are they and how long do Latisse side effects last?

Doctor Answers (19)

There may be potential Latisse side effects


Latisse contains Bimatoprost, a prostaglandin anolog contained in the glaucoma medication, Lumigan. Like Lumigan, potential side effects may be seen, such as darkening of eyelid skin (this may be reversible once stopped).

There may also be a possible increase in the brown pigmentation of the colored part of the eye (this is likely to be permanent).

Other possible side effects may be itching, eye redness, dryness and irritation of the eye or surounding eyelid skin where Latisse may be applied. It is also possible for hair growth to occur in the areas where Latisse comes in contact with. This can be minimized by carefully applying Latisse to the thin strip of eyelid margin skin alone, and blotting any excess solution.

Except for the change in iris color, most side effects will disappear after discontinuing Latisse.

Los Angeles Ophthalmologist
5.0 out of 5 stars 2 reviews

Latisse Side Effects


Fortunately, side effects from Latisse are uncommon. There is no evidence to suggest that Latisse will change your eye color. Over two million prescriptions for Latisse have been filled with no confirmed reports of iris pigmentation issues. Side effects from the initial studies showed less than 4 percent of people experienced redness, irritation and itching of the upper eyelid, which was reversed upon discontinuation.

Mitchell Schwartz, MD
South Burlington Dermatologic Surgeon
5.0 out of 5 stars 8 reviews

Side effects of Latisse


1. Itching of the eyelids

2. Darkening of the iris

3. Darkening of the eyelid skin

4. Worsening of eye diseases such as uveitis, allergic conjunctivitis, iritis.

It is important to have an ophthalmologist check your eyes before and after Latisse usage and to be aware that you are using it. 

Chris Thiagarajah, MD
Washington DC Oculoplastic Surgeon
5.0 out of 5 stars 6 reviews

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Use of Latisse may have minor side effects


Rarely users of Latisse may develop itching of the eyelids.  This resolves when the product is stopped.  There is also the extremely rare incidence of light brown (hazel or green) eyes darkening to a darker brown.  As rare as it this side effect is, it has been reported with the use of the medication as a glaucoma treatment where the medication is put directly in the eye.  In the case of Latisse which is placed on the eyelid and not in the eye, darkening of the eye color is even more rare.  Blue eyes do not turn brown.  This darkening is permanent if it does occur.  Latisse is a really fun and very safe product to use for glamourous lashes.

Elizabeth Slass Lee, MD
Bay Area Plastic Surgeon
5.0 out of 5 stars 33 reviews

Latisse Side effects


Latisse is a prostaglandin analogue similar to the drug bimatoprost used in the treatment of glaucoma.  

Some of the potential side effects are:

1. Darkening of eyelid skin (usually reversible once the drug is stopped)

2. Color change of the iris:  this may occur in lighter colored patients and usually turns the eyes brown.  This is sometimes permanent.

3. Redness and itching which is resolved on discontinuation of the drug.

4. Unwanted hair growth in adjacent areas that come in contact with Latisse.  This can be minimized by apply Latisse carefully only the lash margin of the upper eyelid.

Neil J. Zemmel, MD, FACS
Midlothian Plastic Surgeon
5.0 out of 5 stars 54 reviews

Side Effects of Latisse


Latisse is a prescription medication, which if used  correctly, does not often cause side effects. Nonetheless, we do recommend an eye examination before you initiate treatment and 12 weeks later, as well was yearly after that.  As with any medication, the benefits and risks must be weighed so it is important to use the product correctly and be observed for side effects.

Sandy Feldman, MD
San Diego Ophthalmologist
4.5 out of 5 stars 2 reviews

Latisse Side Effects Eyelid & Eyes


Thicker, longer, darker eyelashes is a goal of a majority of cosmetic patients. Bimatoprost, the active chemical in Latisse, helps to improve the upper eyelashes. Latisse may cause irritation, redness, itching, or hyperpigmentation of the eyelid or eyes. The risk of these is generally low, as long as you follow the application guidelines.

Houtan Chaboki, MD
Washington DC Facial Plastic Surgeon
5.0 out of 5 stars 48 reviews

Latisse Side-Effects

Cosmetically speaking Latisse does have the potential for eyelid darkening which may be reversible after discontinuation of Latisse. I always recommend using the smallest part of the brush and only applying the Latisse to the very top of your lashes.
There is also the potential for increased brown iris pigmentation which is likely to be permanent. Increased iris pigmentation has occurred when bimatoprost solution was administered. Patients with light blue eyes or green would need to be careful of this. 
Potential for unexpected hair growth can also be a side effect if Latisse repeatedly touches the same area of skin outside the treatment area. 

Kristin J. Tarbet, MD
Bellevue Oculoplastic Surgeon
5.0 out of 5 stars 10 reviews

Possible Latisse Side Effects


Bimatoprost (the active compound in Latisse) is a prostaglandin anolog used for the treatment of glaucoma with potential side effects including itching, redness, dry eyes, darkening of eyelid skin or potentially of the iris itself.

Carefull application of Latisse in a thin strip along the eyelid margin skin alone using the provided applicators helps minimizes the risk of side effects.



Dr Quinton Chivers

Quinton Chivers, MD, FRCS(C)
Toronto Plastic Surgeon
3.5 out of 5 stars 3 reviews

The Potential Side Effects of Latisse


This is a very good question.  As with ail prescription medications, there are potential side effects.  However, it is important that the benefits outweigh the potential risks.  In my experience, the most common side effects are: 1. irritation and itching sensation of the eyelids, 2. redness of the eye.  Less common side effects include 1. skin hyperpigmentation (darkening), 2. dryness of the eyes, 3. redness of the eyelids.  These effects have been found to be temporary. Any darkening of the colored part of the eye (the iris) is not expected to reverse.  However, it as been reported to occur in green/hazel colored eyes. Forunately, I have not seen this occur.  I hope this helps.

Leslie M. Sims, MD
Las Vegas Ophthalmologist
5.0 out of 5 stars 2 reviews

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.