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What Are Potential Latisse Side Effects?

Can Latisse cause any side effects I should be aware of?  If so, what are they and how long do Latisse side effects last?

Doctor Answers 25

Side Effects of Latisse

The most common side effects after using Latisse are an itching sensation in the eyes and/or eye redness, skin darkening, eye irritation, dryness of the eyes, and redness of the eyelids. In the original FDA study, about 4% of patients had these side effects. In our experience, nearly all patients tolerate Latisse well. There often is a slight effect of skin darkening along the lash line which is tolerated because it gives the appearance of eyeliner. This slight skin pigmentation resolves once Latisse is discontinued.

There has been information floating around about Latisse changing eye color. First, Latisse was developed from prescription drops used to treat Glaucoma called Lumigan©. Lumigan is an FDA approved eye drop prescription since 2001, meant to be placed directly on the eye daily. In the original Lumigan FDA clinical trials, there was a 1% incidence of hyperpigmentation (or darkening) of the eye color (the iris) in patients with hazel or light brown eyes. In the six years since the release of Latisse there has been NO REPORTED CASES of eye color change due to Latisse that I am aware of. With Latisse the product is applied along the lash line and studies have shown when properly placed, little if any gets on the eye itself. As such, the safety literature that accompanies Latisse mentions this rare risk of a reaction and permanent darkening of your eye color.

Salt Lake City Dermatologic Surgeon
5.0 out of 5 stars 3 reviews

Latisse Side Effects

Fortunately, side effects from Latisse are uncommon. There is no evidence to suggest that Latisse will change your eye color. Over two million prescriptions for Latisse have been filled with no confirmed reports of iris pigmentation issues. Side effects from the initial studies showed less than 4 percent of people experienced redness, irritation and itching of the upper eyelid, which was reversed upon discontinuation.

Mitchell Schwartz, MD
South Burlington Dermatologic Surgeon
5.0 out of 5 stars 10 reviews

Side effects of Latisse

1. Itching of the eyelids

2. Darkening of the iris

3. Darkening of the eyelid skin

4. Worsening of eye diseases such as uveitis, allergic conjunctivitis, iritis.

It is important to have an ophthalmologist check your eyes before and after Latisse usage and to be aware that you are using it. 

Chris Thiagarajah, MD
Denver Oculoplastic Surgeon
5.0 out of 5 stars 7 reviews

Latisse Side effects

Latisse is a prostaglandin analogue similar to the drug bimatoprost used in the treatment of glaucoma.  

Some of the potential side effects are:

1. Darkening of eyelid skin (usually reversible once the drug is stopped)

2. Color change of the iris:  this may occur in lighter colored patients and usually turns the eyes brown.  This is sometimes permanent.

3. Redness and itching which is resolved on discontinuation of the drug.

4. Unwanted hair growth in adjacent areas that come in contact with Latisse.  This can be minimized by apply Latisse carefully only the lash margin of the upper eyelid.

Side Effects of Latisse

Latisse is a prescription medication, which if used  correctly, does not often cause side effects. Nonetheless, we do recommend an eye examination before you initiate treatment and 12 weeks later, as well was yearly after that.  As with any medication, the benefits and risks must be weighed so it is important to use the product correctly and be observed for side effects.

Sandy Feldman, MD
San Diego Ophthalmologist
4.5 out of 5 stars 2 reviews

Latisse Side Effects Eyelid & Eyes

Thicker, longer, darker eyelashes is a goal of a majority of cosmetic patients. Bimatoprost, the active chemical in Latisse, helps to improve the upper eyelashes. Latisse may cause irritation, redness, itching, or hyperpigmentation of the eyelid or eyes. The risk of these is generally low, as long as you follow the application guidelines.

Houtan Chaboki, MD
Washington DC Facial Plastic Surgeon
5.0 out of 5 stars 65 reviews

There may be potential Latisse side effects

Latisse contains Bimatoprost, a prostaglandin anolog contained in the glaucoma medication, Lumigan. Like Lumigan, potential side effects may be seen, such as darkening of eyelid skin (this may be reversible once stopped).

There may also be a possible increase in the brown pigmentation of the colored part of the eye (this is likely to be permanent).

Other possible side effects may be itching, eye redness, dryness and irritation of the eye or surounding eyelid skin where Latisse may be applied. It is also possible for hair growth to occur in the areas where Latisse comes in contact with. This can be minimized by carefully applying Latisse to the thin strip of eyelid margin skin alone, and blotting any excess solution.

Except for the change in iris color, most side effects will disappear after discontinuing Latisse.

Shalini Kapoor, MD
Los Angeles Ophthalmologist
5.0 out of 5 stars 2 reviews

Common Latisse Side Effects

Latisse is an FDA approved prescription treatment for hypotrichosis (inadequate or not enough lashes) and is effective at helping lashes grow longer, fuller and darker.
The most common side effects when using Latisse is eyelid skin darkening and is reversible when discontinuing usage of Latisse, this eyelid darkening is similar in appearance a light brown eye liner having just been drawn on. Other common side effects are itchy and red eyes. However, this depends on the patient; we have many patients with very sensitive eyes that have never experienced those side effects when using Latisse. For patients that do experience itchy red eyes when using Latisse, we typically find that after several weeks of initial usage, any itchy or redness has subsided or stopped. For optimal results discuss this with the prescribing physician or staff members to further aid you in the process.

Frank Barone, MD
Toledo Plastic Surgeon
5.0 out of 5 stars 32 reviews

Anticipate Minimal Side Effects

It’s unusual to see complications following the use of Latisse. Fortunately, when complications do occur they tend to be self-limited.Common complications include eye irritation, eye redness, eyelid itching and eyelid hyperpigmentation.These usually resolve when Latisse is discontinued.
In patients with light colored irises Latisse can rarely change the iris color to brown.Unfortunately, this is probably a permanent change.If any of these problems occur it’s important to notify your physician as soon as possible.

Latisse Side Effects

The most common side effects of Latisse are an allergic or irritant reaction that can cause redness, swelling, dryness, and/or itchiness around the eyes. It is important not to get the product in your eyes. As long as you follow the application guidelines, these risks are typically low. 

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.