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What Are Potential Latisse Side Effects?

Can Latisse cause any side effects I should be aware of?  If so, what are they and how long do Latisse side effects last?

Doctor Answers 22

There may be potential Latisse side effects

Latisse contains Bimatoprost, a prostaglandin anolog contained in the glaucoma medication, Lumigan. Like Lumigan, potential side effects may be seen, such as darkening of eyelid skin (this may be reversible once stopped).

There may also be a possible increase in the brown pigmentation of the colored part of the eye (this is likely to be permanent).

Other possible side effects may be itching, eye redness, dryness and irritation of the eye or surounding eyelid skin where Latisse may be applied. It is also possible for hair growth to occur in the areas where Latisse comes in contact with. This can be minimized by carefully applying Latisse to the thin strip of eyelid margin skin alone, and blotting any excess solution.

Except for the change in iris color, most side effects will disappear after discontinuing Latisse.

Los Angeles Ophthalmologist
5.0 out of 5 stars 2 reviews

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Latisse Side Effects

Fortunately, side effects from Latisse are uncommon. There is no evidence to suggest that Latisse will change your eye color. Over two million prescriptions for Latisse have been filled with no confirmed reports of iris pigmentation issues. Side effects from the initial studies showed less than 4 percent of people experienced redness, irritation and itching of the upper eyelid, which was reversed upon discontinuation.

Mitchell Schwartz, MD
South Burlington Dermatologic Surgeon
5.0 out of 5 stars 9 reviews

Side effects of Latisse

1. Itching of the eyelids

2. Darkening of the iris

3. Darkening of the eyelid skin

4. Worsening of eye diseases such as uveitis, allergic conjunctivitis, iritis.

It is important to have an ophthalmologist check your eyes before and after Latisse usage and to be aware that you are using it. 

Chris Thiagarajah, MD
Washington DC Oculoplastic Surgeon
5.0 out of 5 stars 6 reviews

Use of Latisse may have minor side effects

Rarely users of Latisse may develop itching of the eyelids.  This resolves when the product is stopped.  There is also the extremely rare incidence of light brown (hazel or green) eyes darkening to a darker brown.  As rare as it this side effect is, it has been reported with the use of the medication as a glaucoma treatment where the medication is put directly in the eye.  In the case of Latisse which is placed on the eyelid and not in the eye, darkening of the eye color is even more rare.  Blue eyes do not turn brown.  This darkening is permanent if it does occur.  Latisse is a really fun and very safe product to use for glamourous lashes.

Elizabeth Slass Lee, MD
Bay Area Plastic Surgeon
5.0 out of 5 stars 35 reviews

Latisse Side effects

Latisse is a prostaglandin analogue similar to the drug bimatoprost used in the treatment of glaucoma.  

Some of the potential side effects are:

1. Darkening of eyelid skin (usually reversible once the drug is stopped)

2. Color change of the iris:  this may occur in lighter colored patients and usually turns the eyes brown.  This is sometimes permanent.

3. Redness and itching which is resolved on discontinuation of the drug.

4. Unwanted hair growth in adjacent areas that come in contact with Latisse.  This can be minimized by apply Latisse carefully only the lash margin of the upper eyelid.

Side Effects of Latisse

Latisse is a prescription medication, which if used  correctly, does not often cause side effects. Nonetheless, we do recommend an eye examination before you initiate treatment and 12 weeks later, as well was yearly after that.  As with any medication, the benefits and risks must be weighed so it is important to use the product correctly and be observed for side effects.

Sandy Feldman, MD
San Diego Ophthalmologist
4.5 out of 5 stars 2 reviews

Latisse Side Effects Eyelid & Eyes

Thicker, longer, darker eyelashes is a goal of a majority of cosmetic patients. Bimatoprost, the active chemical in Latisse, helps to improve the upper eyelashes. Latisse may cause irritation, redness, itching, or hyperpigmentation of the eyelid or eyes. The risk of these is generally low, as long as you follow the application guidelines.

Houtan Chaboki, MD
Washington DC Facial Plastic Surgeon
5.0 out of 5 stars 58 reviews

Side Effects are very uncommon

The most common side effects after using LATISSE solution are an itching sensation in the eyes and/or eye redness.

George T. Boris, MD, FRCS, FACS
Los Angeles Facial Plastic Surgeon
4.0 out of 5 stars 13 reviews

Latisse side effects

Side effects of Latisse:

darkening of the skin in the area
eye dryness

One very rare risk is an increase in brown pigmentation in the irises in green or hazel eyes. However, I haven't seen this occur with any of my patients to date.

Side Effects of Latisse

The most common side effects after using Latisse are an itching sensation in the eyes and/or eye redness, skin darkening, eye irritation, dryness of the eyes, and redness of the eyelids. In the original FDA study, about 4% of patients had these side effects. In our experience, nearly all patients tolerate Latisse well. There often is a slight effect of skin darkening along the lash line which is tolerated because it gives the appearance of eyeliner. This slight skin pigmentation resolves once Latisse is discontinued.

There has been information floating around about Latisse changing eye color. First, Latisse was developed from prescription drops used to treat Glaucoma called Lumigan©. Lumigan is an FDA approved eye drop prescription since 2001, meant to be placed directly on the eye daily. In the original Lumigan FDA clinical trials, there was a 1% incidence of hyperpigmentation (or darkening) of the eye color (the iris) in patients with hazel or light brown eyes. In the six years since the release of Latisse there has been NO REPORTED CASES of eye color change due to Latisse that I am aware of. With Latisse the product is applied along the lash line and studies have shown when properly placed, little if any gets on the eye itself. As such, the safety literature that accompanies Latisse mentions this rare risk of a reaction and permanent darkening of your eye color.

David J. Myers, MD
Salt Lake City Dermatologic Surgeon
5.0 out of 5 stars 3 reviews

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.