Can Latisse Permanently Darken the Skin of my Eyelids?

Latisse can darken and/or redden the skin in the area where it is applied, but it's temporary and will go away after you stop using it.

Latisse is a wonderful product and my patients are thrilled with the results. A very infrequent side effect is pigment change (darkening) of the eyelid skin. I have only seen this in one patient and it should resolve if the product is discontinued. There are no reports of Latisse changing the color of the iris of the eye. When it was used as a Glaucoma medication, it was applied as an eye drop and had a rare side effect of eye color change. Latisse should only be applied to the upper eyelid once daily at bedtime, and you should stop using it if any irritation (another possible side effect) or discoloration develop. If you have Glaucoma, you should check with your eye doctor before using Latisse.

Latisse has been reported to cause increased pigmentation of the eyelid skin. In most cases the pigment disappeared when Latisse use was stopped.

Latisse may also cause irreversible darkening of light colored eyes.

These side effects, as well as any pre-existing ocular conditions should be discussed with your physician  before using Latisse.