Ask a doctor

Can I Have Botox on my Forehead and Xeomin on my Glabella?

I was considering having my glabella and forehead done two days apart by two different physicians. Would it be okay to have xeomin in one area and botox in another?

Doctor Answers 25

Two different BTX-As at different places in face

There is nothing inherentky wrong with using different BTX-As on the same day or different days in different areas. I often use more than one on the same day in different areas because of the unique characteristics of each product such as more or less diffusion, earlier or late onset of effect.

One caution I would share, however, is that your brow can become flattened for a week or two if you do not have the glabellar complex (frown lines) treated first, and then wait a week or more before treating the furrows across the brow.  By waiting to inject, the brows can stay elevated and the patient can save money by only injecting the forehead where still needed. The downside to this, of course, is having to go twice but my patients are uniformly happy that they never get a depressed eyebrow and pay for fewer units of the medication.

And you may invite unexpected side effects if you do not have the treatments with the same dermatologist.  Thus is not only because the right hand will not know exactly what the left hand has done (and will not be able to extrapolate by looking at the result since you were only allowing 2 days in-between), but also because every patient's face is unique, and an advanced and skilled physician will develop a treatment pattern and frequency that matches that patient's needs and responses to prior injections.

New York Dermatologist
5.0 out of 5 stars 3 reviews

Have a question? Ask a doctor

Combining neurotoxins

There is no issue combining different brands of neurotoxin, including xeomin, dysport, or botox, on the same day or separating the injection by a few days. Your outcome, however, may be compromised if the right hand (second physician) doesn't know what the left hand (first physician) injected.

Ramona Behshad, MD
Saint Louis Dermatologic Surgeon
5.0 out of 5 stars 5 reviews

Botox and Xeomin Combination

The simple answer is yes – the real answer is to ask you why you are going to two different providers to have these medicines injected? And two days apart – that is not the smartest thing to do as the effects of one have not had time to take full effect and the second procedure, which can be done on the same day as the first, may be over-treated or under-treated without the same provider doing all the work.

I think you need to reevaluate what you are doing; find a board-certified dermatologist or plastic surgeon, and do things right the first time with one provider.

Michael Gold, MD
Nashville Dermatologic Surgeon
4.5 out of 5 stars 10 reviews

You might also like...

Combining Botox and Xeomin

There is no reason that you can't combine Botox and Xeomin.  However when treating a patient with those products the whole face is taken into account.  So if you want to have it done by two different doctors I would wait two weeks so that the effects of the first are there and the second doctor does not over inject you.  Good Luck.

Jessica Lattman, MD
New York Oculoplastic Surgeon
5.0 out of 5 stars 8 reviews

Can I Have Botox on my Forehead and Xeomin on my Glabella?

You can, but the question is: why? Mixing neurotoxins in and of itself is not dangerous. However, with two different surgeons administering only a couple of days apart, you may run into a problem of overlap/double dosing in some areas. I would stick with one provider for treatment consistency.

Eric Desman, MD
Alexandria Plastic Surgeon
5.0 out of 5 stars 5 reviews


Thank you for your question.

Botox and Xeomin should not interfere with one another.

To be sure, see two or more board certified and experienced plastic surgeons in your area for a full and complete evaluation.

I hope this helps.

J. Jason Wendel, MD, FACS
Nashville Plastic Surgeon
5.0 out of 5 stars 51 reviews

Are two toxins better than one?

There should not be any problem having your glabella injected with one neurotoxin such as Xeomin and then having your forehead injected with Botox.  Not sure what the reasoning would be to split the treatments up between doctors and with different toxins.  Your would probably be best served with the most experienced injector.

Jerome Potozkin, MD
Danville Dermatologic Surgeon
4.0 out of 5 stars 5 reviews

Xeomin injections in Los Angeles

There should not be any problems mixing the two products. However, it is advisable to stick to one of the two injectables at any given time. I do not see the benefits of mixing the two injections. Raffy Karamanoukian Los Angeles

Raffy Karamanoukian, MD, FACS
Los Angeles Plastic Surgeon
5.0 out of 5 stars 57 reviews

Can I Have Botox on my Forehead and Xeomin on my Glabella?

There wouldn't be any issue combining different neurotoxins to different areas on the face. I advise to find one physician you are comfortable with to do all treatments to avoid any confusion. 

Can I Have Botox on my Forehead and Xeomin on my Glabella?

Yes, you can. There are no problems that I am aware of in mixing neuromodulators, such as Botox, Dysport and Xeomin in different parts of the face or body.  It is the total combined units that counts.  I would be less comfortable with injecting an area that had just been injected, since there may be additional swelling or bruising from the initial injection. 
I hope that this helps and good luck,

Dr. E

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.