A large number of injectable fillers are now available for the treatment of facial wrinkles and contour irregularities. These fillers are especially helpful for treating thin lips, nasolabial folds and marionette lines. The best injectable filler is the subject of intense debate amongst plastic surgeons. Although most surgeons have preferences regarding their filler of choice, all agree that the choice of filler needs to be individualized based on the patient’s needs.When picking a filler material several variables should be considered. These include how long the fillers will last, the amount of filler needed, the location of the injection, and the skin type to be injected. Based on these considerations, results can be optimized for the majority of patients by choosing the right filler material.Several dermal filler options are available for patients with facial wrinkles and contour irregularities. These include both Juvederm and Radiesse.In most situations, hyaluronic acid fillers such as Juvederm are the treatment of choice for facial wrinkles. These fillers are highly effective and very safe. They can also be reversed with hyaluronidase if patients aren’t satisfied with their results. In most cases, they last for 6 to 9 months and may last up to a year following injection. Because of their versatility they are currently the gold standard for injectable fillers.Radiesse is a synthetic filler that contains hydroxyapatite particles. It last for longer periods of time and may actually stimulate collagen growth. It may be associated with significant complications including inflammation, infection, granuloma formation, and scarring. For these reasons Radiesse has limited applications for treating facial contour issues.If you’re considering treatment of facial wrinkles, it’s important to consult a surgeon with experience in this area. This surgeon should be able to determine which filler is best for you.