Juvederm or Restylane to fill in forehead lines is off-label like many other uses of these products. I routinely use fillers in forehead lines that do not respond completely to Botox. I have used Juvederm, Restylane, Radiesse, Evolence, Elevess on scores of patients with no complications. I think the risk of skin necrosis (barring intravascular injection) is extremely small if the product is injected intradermally by an injector experienced in this area.



