POSTED UNDER Xeomin Reviews
Developed an Immunity to Botox and Immune to Xeomin - Newmarket, ON
UPDATED FROM Astrid Stellar
1 year post
May try Dysport
Astrid StellarMay 7, 2016
$1,100
I have an appointment to try Dysport next week. However, after reading the latest literature, I am not hopeful. F.Y.I: The same article does say that they have been successful treating people resistant to type A toxins. It involves transplanting plasma. The article can be found on the internet. It is titled "Neutralizing antibodies to botulinum neurotoxin type A in aesthetic medicine: five case reports. It is in the journal, Clinical, Cosmetic and Investigational Dermatology. I am guessing that you would have to be quite affluent to have this done.
Replies (2)
October 14, 2022
This is me too. I’ve developed the immunity the last year and im struggling to find something to work again. I tried xeomin and nothing. Im going to try dysport next and then try myobloc if that still dosent work. This sucks!!!
ORIGINAL POST
I started using Botox at least 15 years ago. I...
Astrid StellarJuly 14, 2015
I started using Botox at least 15 years ago. I began with modest amounts of units with great results. I then wanted the frozen, wrinkles look for my forehead. I was given 45 units. It was spectacular and lasted 6 months. The next time, I received the same amount. I was fighting a flu at the time of the injection. The results only lasted 4 months. The doctor was concerned I was developing an immunity at a time when immunity was denied by the makers of Botox. The next time, I again received 45 units. It did not work. I tried 3 other doctors, using fresh bottles and no results. I went up to 80 units and no results. When Xeomin arrived, I was very excited, The doctor thought it would work as there is no/less protein in Xeomin. However, he warned that it an assumption that people who developed an immunity to Botox did so, because of the protein. He said there is one other possibility, the immunity is to the coating. After a total of 90 units of Xeomin, I had full movement of muscles on my forehead. The doctor said I am the only person he met who truly has an immunity. He thinks I developed it, when I received treatment when I had the flu. While my body was building immunity to the virus, it may have been confused and developed an immunity to the Botox?????? In my case the coating and not the protein??? Bad luck! I am so jealous of everyone else.
Replies (4)

July 17, 2015
Hi cbpi, thanks for postiing! Wow, I'm sorry to hear you've developed an immunity. I read that it's pretty rare, but that other methods can be used to achieve similar results. Besides the Xeomin, have you researched or tried other methods? Is Dysport a possibility?
July 17, 2015
I have been told that I will likely an immunity to any Botulinum "A" strand, although I have not tried Dysport (A type). There is MyoBloc. It is my understanding that it is a "B' strand. Unfortunately, I have not been able to find anyone in Canada offering this option.
August 31, 2015
This is me!!! I've tried botox, dysport and xeomin. None of them work on me any longer, and three different injectors have told me I'm a medical miracle. I think it's more likely that our situation will become more common spread, and resistance hasn't been documented enough to know how commonly it's probably already occurring. I'm currently trying to locate someone who can inject Myobloc...it's Botulinum Type B vs Type A, and it gas been found to have results in those shoeing resistance to Type A. It's just near impossible where I am to find it! But I'm not giving up!! I have aged five years since the last remnants of my Type A wore off 11 months ago. Sigh, I do love being exceptional mostly, just I'd prefer not to be when botox is involved.
May 23, 2017
This is me too! I have a feeling this is going to turn out to be more common as the years go on.. My Dr. is already seeing it more and more.
September 22, 2017
I was told yesterday that there will be new solutions on the market within the year as this problem has become increasingly common.
September 23, 2017
Wow, that's certainly encouraging! as I really feel hopeless... I'd appreciate any information you have regarding the new solutions. Thanks!
October 14, 2022
Can any of you please update me if you have found any treatments that have worked for your immunity!
It gives me hope.