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POSTED UNDER Xeomin Reviews

Developed an Immunity to Botox and Immune to Xeomin - Newmarket, ON

UPDATED FROM Astrid Stellar
1 year post

May try Dysport

$1,100
I have an appointment to try Dysport next week. However, after reading the latest literature, I am not hopeful. F.Y.I: The same article does say that they have been successful treating people resistant to type A toxins. It involves transplanting plasma. The article can be found on the internet. It is titled "Neutralizing antibodies to botulinum neurotoxin type A in aesthetic medicine: five case reports. It is in the journal, Clinical, Cosmetic and Investigational Dermatology. I am guessing that you would have to be quite affluent to have this done.

Astrid Stellar's provider

York Vein and Laser Clinic

Replies (2)

did Dysport work for you? I, too, have developed resistance to Botox, as I've been using it for masseter muscle reduction for the past 11 years. I tried Dysport a few weeks ago and it didn't work at all... so I went with Xeomin (60 units total 30 on each side of the jaw muscle) a week and a half ago.... so far I have not seen or felt any difference in the muscle....I'm very very disappointed and feel pretty hopeless.... it's not even the money (though I am not rich, I'm willing to spend money as long as it works)....but nothing works for me anymore.... very depressed....
None of these work on me anymore. The longest any of these last on me is 4 weeks. Big bummer. However every Dr I go to swears that I am the only one.
well you're not the only one.... the xeomin and dysport didn't work AT ALL
I was waiting to post until I was sure of my results ... Xeomin did nothing for me even after increasing the units and trying different doctors. So, after reading the article that I mentioned in one of my earlier posts....I did not expect Dysport to work. However, it did. I have had it administered twice. The first time lasted longer but it was administered to different areas in my forehead the second time. I will be going for my third treatment soon....Why did it work? I am not a scientist so, I don't know...Nevertheless, here comes the hocus pocus factor....I did several hydrotherapy colonics and Myers Cocktail drips (intravenous vitamins) prior to the administration of Dysport. Although there is NO substantial evidence that it can change blood plasma...some naturopaths claim it does. As well, there had been a significant waiting period between the last administration of Xeomin and Dysport. As to whether I will develop an immunity to Dysport too...only time will tell.
I have this very same experience!! Every Dr I go to swears that I am the only one. And I am so disappointed :-(
Thank You for sharing your experience.
It gives me hope.
Is dysport still working for you?
This is me too. I’ve developed the immunity the last year and im struggling to find something to work again. I tried xeomin and nothing. Im going to try dysport next and then try myobloc if that still dosent work. This sucks!!!
ORIGINAL POST

I started using Botox at least 15 years ago. I...

I started using Botox at least 15 years ago. I began with modest amounts of units with great results. I then wanted the frozen, wrinkles look for my forehead. I was given 45 units. It was spectacular and lasted 6 months. The next time, I received the same amount. I was fighting a flu at the time of the injection. The results only lasted 4 months. The doctor was concerned I was developing an immunity at a time when immunity was denied by the makers of Botox. The next time, I again received 45 units. It did not work. I tried 3 other doctors, using fresh bottles and no results. I went up to 80 units and no results. When Xeomin arrived, I was very excited, The doctor thought it would work as there is no/less protein in Xeomin. However, he warned that it an assumption that people who developed an immunity to Botox did so, because of the protein. He said there is one other possibility, the immunity is to the coating. After a total of 90 units of Xeomin, I had full movement of muscles on my forehead. The doctor said I am the only person he met who truly has an immunity. He thinks I developed it, when I received treatment when I had the flu. While my body was building immunity to the virus, it may have been confused and developed an immunity to the Botox?????? In my case the coating and not the protein??? Bad luck! I am so jealous of everyone else.

Replies (4)

Hi cbpi, thanks for postiing! Wow, I'm sorry to hear you've developed an immunity. I read that it's pretty rare, but that other methods can be used to achieve similar results. Besides the Xeomin, have you researched or tried other methods? Is Dysport a possibility?

I have been told that I will likely an immunity to any Botulinum "A" strand, although I have not tried Dysport (A type). There is MyoBloc. It is my understanding that it is a "B' strand. Unfortunately, I have not been able to find anyone in Canada offering this option.
This is me!!! I've tried botox, dysport and xeomin. None of them work on me any longer, and three different injectors have told me I'm a medical miracle. I think it's more likely that our situation will become more common spread, and resistance hasn't been documented enough to know how commonly it's probably already occurring. I'm currently trying to locate someone who can inject Myobloc...it's Botulinum Type B vs Type A, and it gas been found to have results in those shoeing resistance to Type A. It's just near impossible where I am to find it! But I'm not giving up!! I have aged five years since the last remnants of my Type A wore off 11 months ago. Sigh, I do love being exceptional mostly, just I'd prefer not to be when botox is involved.
This is me too! I have a feeling this is going to turn out to be more common as the years go on.. My Dr. is already seeing it more and more.
I was told yesterday that there will be new solutions on the market within the year as this problem has become increasingly common.
Wow, that's certainly encouraging! as I really feel hopeless... I'd appreciate any information you have regarding the new solutions. Thanks!
Can any of you please update me if you have found any treatments that have worked for your immunity!
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