I had Artefill in December of 2008. Two syringes in the nasolabial folds, more in the right side than left. I am very happy with the results. I noticed immediate improvement, with slightly more over the next three months. I have not had any adverse reactions and the improved has been permanent so far - I've been told that "long lasting" is the phrase used now. I beIieve the time frame they state is 3-5 years. One thing I did do was go back for the second syringe even though the provider told me that "no one is perfect". That's true, but I knew what I wanted and the first syringe wasn't enough to even out both sides of my face. I was right.
I look in the mirror about 70% less than before I got the treatments, because I'm not worried about how my mouth looks.
I would recommend it to anyone, with the advice of using an experienced doctor with a long history of doing fillers, Artefill in particular.