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POSTED UNDER Spironolactone For Acne REVIEWS

Trying Spironolactone...because I've Basically Tried Everyting Else.

ORIGINAL POST

So, in my endless struggle with acne I've finally...

Megan P
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This reviewer is affiliated with RealSelf. The views expressed here are their own and do not reflect the views of RealSelf, Inc.

So, in my endless struggle with acne I've finally decided to try Spironolactone. It was suggested to me by my dermatologist about a year ago, but when I did my research and found out it was a blood pressure medication being used off label for acne I said no way! Then...the I had a big increase in stress in my life and the breakouts got worse, and worse, and worse. I was to the point that I wasn't wanting to go to the gym in the morning because I dreaded having people see my skin without makeup on, and I skipped an event I had really wanted to go to because I was so embarrassed of the way my skin was looking.

I was started on 100mg of Spironolactone about 2.5 months ago. From the time I started taking the medicine I noticed myself not feeling great. I was lower on energy, and my endurance when running was about 3/4 of what it usually was. After taking it for about a month I started noticing little tiny "flutters" from my heart. Then, on a trip to the east coast with a very dear friend who also happens to be a anesthesiologist I had what he called a "vagal response" aka nearly passed out on the subway. Due to those things I decided to half my dose and am now taking 50mg's a day. At that point I had already had my blood tested to check my potassium levels, as this drug is known to retain potassium in the body, and my levels came back fine.

Overall I feel much better with the lower dose. I have definitely seen a decrease in my acne and hope that will continue to be the case even with the lower dose. 

Also, I do want to mention that I tend to have low blood pressure as is, and have fainted for unexplainable reasons in the past, so what I experienced during my trip isn't a completely foreign thing to me. It has been about two years since something like that has gone on though, so I'm not sure how much of it had to do with the Spironolactone and how much of it is just my weird little body!

Hopefully I'll see even better clearing of my skin soon!

Updated 12/6/12

I'm still taking 50mg's of Spiro a day. Unfortunately I have had a bit more breakouts over the last couple of weeks. Its been pretty small pimples, with much less of the large cystic type. That is definitely an improvement from before I was on Spiro, but not as good as the results I was seeing when I was on 100mg's. My derm's office said to let them know if I wanted to try 75mg, but honestly since I still don't feel great with the 50mg I'm not sure I want to up it any. Of course I do want to up it to get more clearing of my skin, but will stick with 50mgs for now and see what goes on. Ugh...seriously so sick of dealing with acne. I feel like it should be gone by the age I am now. Will continue to update as I see changes.

Updated 12/10/12

My skin continued to break out over the weekend. I'm going to give the Spiro at 50mg another month and hope things clear up, and this was just an "adjustment" phase...but I'm thinking the 100mgs is what would be needed to help, and I just don't think being on 100mg is worth it to me with the side effects I experienced. Lame.

Updated 1/9/12

I ended up going completely off the Spiro about a week or two ago. Of course I sick (completely unrelated) shortly there after so I haven't done my regular workouts for about a week. I'm hoping to start working out again later this week, and within a couple weeks I'm thinking I will have a good idea of how much the spiro was affecting my endurance. I'm nervous to even write this, but so far my skin has been remaining pretty clear. Its the week before my period too...but since I've been sick I haven't been wearing makeup so that might be helping. Guess we'll see what happens when I get back to my normal routine soon.

Replies (28)

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December 7, 2012
I tried Spiro...loved that it made me face less oily and as a result my acne improved; however I stopped taking it because it started causing me to have an irregular heartbeat (scary!)
December 7, 2012

Yeah, it is scary. I'm glad you listened to your body and realized it wasn't right for you! I looked on your profile for reviews to see what you are taking now, but didn't see any. From the comments you've posted it sounds like you have some definite experience to share. I'd love it if you would post reviews so we can hear the full scoop on what you have tried. :)

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February 12, 2013
try lime juice, if it burns ur skin it means ur hav a lot of bacteri in your skin, it works right there an then u put the lime juice on let it dry, apply another layer an leave on for 15 mins.
February 12, 2013

Huh, I'll have to try it. I would love to find something natural to help! :)

December 7, 2012
I have never heard or tried this medication and because of the low blood pressure issue I'd get a second opinion. Is it an antibiotic or a gel/cream? If you're not seeing results try Solodyne and Acanya...I've had great results with these two together. I had a friend who had acne and he suffered from nightmares and dreams that made him feel like he was flying. I believe he was taking Accutane. Nevertheless after months on the medication his skin started to get spotty and glassy like and he had to stop taking it. Long story short he still has those nightmares and worse still has the acne. My point is don't be afraid to seek a second opinion if you're not seeing results or feel the medicine is causing problems. It took me 3 different doctors to find the right one. GOOD LUCK!
December 7, 2012

Seeking a second opinion is ALWAYS good advice in my book, so thank you for encouraging that.

Spironolactone is taken in pill form. I definitely researched it out, even down to asking my OB/GYN about the effects it could have on my hormones (as that is how it helps the acne) before going on it. 

From what I understand Solodyne is a form of the antibiotic minocycline. When I was much younger I tried a few different antibiotics and I always found that they worked great for a bit of time (3-9 months) then the acne would just come back. :-/

I haven't tried Acanya, but I have tried benzoyl peroxide and clindamycin on their own (from what I understand Acanya is a combo of the two) and again, I had good results for a bit then the acne just came back. Argh!!

Do you mind me asking how long you have been on that combo? Hopefully you have had longer term success with those treatments than I did.

 

December 8, 2012
So after taking Spiro for nearly 2 weeks, I've decided to stop. I've just been lethargic to the point of feeling sad all day. Also, since I'm taking Tretinoin gel now, it's best to only be on one medication because it's impossible to know which agent is responsible for the changes I'm seeing.
December 8, 2012
I also wanted to ask, since you've been on Acutane and Retin-A gel and the like, have you tried birth control pills?
December 10, 2012

Yeah, I think the BCP's help some but unfortunately isn't enough to completely eliminate my acne. :-/

December 10, 2012
Hi Megan, How long does your dr recommend u stay on spiro? Thx
December 10, 2012

We didn't really discuss an end point. At this time I have refills for a year, then we would re-evaluate at that time I guess.