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POSTED UNDER Hyaluronidase REVIEWS

Hyaluronidase Nightmare - Permanent Damage to Lower Eyelid Tissue?

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10/08 juvederm in tear troughs for eyebags/dark...

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tried but failed
$500

10/08 juvederm in tear troughs for eyebags/dark circles (looked great). 04/17/09 restylane in tear troughs (top up). Unhappy with the result. 06/15/09 dissolved with hyaluronidase. All product dissolved. Big mistake! Within hours of the hyaluronidase injections my lower eyelids were terribly swollen (like large bags of water) and black - much worse than original bags.
I used Advantan steroid cream in case it was an allergy to the hyaluronidase. Not much improvement in the swelling. 06/26/09 juvederm ultra put in tear troughs because it looked so bad that I had to do something. Product was placed the same as in Oct 08, but has not had the same effect. In Oct 08 the juvederm corrected the puffiness and bags and felt 'firm' under the skin. This time the puffines and bags are still there despite the juvederm.
The skin feels spongy and there is a layer of jelly-like fluid across both of my lower eyelids, including over the juvederm (I can feel the product beneath the spongy layer). I have used all of the recommended treatments for eyelid edema - ice, cold compress, warm compress, bruise/swelling cream, caffeine lotion etc etc etc. I sleep with my head elevated. Nothing works. The puffiness and swelling remain. My left side is particularly bad.
What should I do to resolve the puffiness and swelling in the lower eyelids? Will it resolve over time? If so, how long should I expect to wait? Or has the hyaluronidase done irreversible damage to the tissue of my lower eyelids and the edema is therefore permanent? There is not much information about hyaluronidase on the internet. I look ghastly. Please help.

Replies (149)

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July 5, 2009
Clearly I meant to tick the NOT worth it icon. RealSelf, can you please amend this? Thanks
July 6, 2009

you bet.  we made the change.  thanks for posting

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August 9, 2009
Wow, your results to this procedure sounds awful. I am sorry that you are having such awful results. Why did you change from the juvederm to the restylane if the juvederm worked well to begin with (just wondering if the doc suggested the change or if was cost issue?)? Have you gotten a 2nd opinion on what could be done to help the swelling? I do hope you find something or someone that can help you with this problem. Best, Chrystal Eckes
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August 9, 2009
messed up on that Just Wondering part: I was wondering if the doc suggested the change or if it was a cost issue or savings?
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August 9, 2009
Hey, under this post: http://www.realself.com/review/Juvederm-hyaluronidase-gave-me-water-balloons-under-my-eyes She said that she took steroids and it helped the swelling. Maybe that is something to look into.
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August 11, 2009

Hi Chrystal - the doctor gave me the Restylane WITHOUT ASKING ME if I wanted to try a different product. I had no idea it was Restylane (and not Juvederm) until I paid the bill! I am no longer concerned about the hyaluronidase nightmare - read my botox review and you will see why. The doctor thought she could 'fix' the swollen appearance under my eyes from the hyaluronidase with botox. I was so depresssed about how I looked that it did not even occur to me to ask the rational question: HOW is botox going to help swelling? Of course paralysing the eye muscles only makes swelling worse because it further diminishes the pump action around the eyes which clears fluid. To make matters worse, my skin had all broken out from the stress of the hyaluronidase fiasco so the doctor put me on antibiotics (tetracycline antibiotics called Doxycycline). I had been taking them for 18 days before the botox and then took them for 7 days after the botox. Tetracycline antibiotics are contraindicated with botox. They increase the physical effect and the side effects of botox. The doctor claimed she 'didn't know' that you are not supposed to administer botox and tetracycline antibiotics at the same time. I found it in THREE SECONDS on the internet. The Allergan literature says that certain antibiotics may potentiate the effect of botox. The physical effect on my face is awful and it was already no good from the hyaluronidase. I am seeing a plastic surgeon next week who has a sub-specialty in facial paralysis to see if he can help me make this horrible disaster on my face recover more quickly. My whole face has dropped like I have had a stroke. I simply cannot see how my poor weakened eye muscle is going to be able to pull all of my facial fat back up my face. It will need some help. The eye muscles are still completely paralysed, so it is going to be a long time before I see any improvement whatsoever.

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August 11, 2009
I am so sorry that this has happened to you. You are brave to share your story with the world. Thank you. It just goes to show you that you have to really watch the doctors and ask questions relentlessly. I don't understand why the doctor would change without consulting with you first! This is another unforgivable excuse -- she has caused you harm and what if anything has she offered to do to help with your disaster??? I do hope that you find someone who can help you. Best, chrise.
June 15, 2012
Dont know if your out there still sweetie but, let me tell you what happened to you. The substance you received is a naturally accuring substance manufactued in our skin/body however, this substance destroys your skin collagans along with collagan III. In fact that is the very thing (hyalurondase) that increases through the aging process and collagan III is depleated In young skin there is a abundance of collagan III....Im sorry this happened to you. Your cells are made by the food you eat every hour of every day, and not anything else. Eat bad stuff, get bad cells. sorry you were a victom of malpractice!!!
November 24, 2012
In what tests or liturature does it show that Hyalorondase depletes your own collagan. Not saying it doesn't as I now have scars on my chin where she took out Juvederm that I did not ask for. Looks like I have 3 rivers and orange peel like skin. Is there any way to fix with collegan etc or lazers that stimulate collagen or is this area ruined?
June 13, 2015
How are you today, has your own collage rebuild?
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August 11, 2009
Oh and by the way, the Restylane was MORE expensive than Juvederm!!
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August 12, 2009

Thanks for your support Chrystal - although I am very angry that Restylane was used instead of Juvederm without my permission, after reading the diabolical reviews of Radiesse and Sculptra (particularly under the eyes) I feel lucky that she didn't decide to use either of these products on me. Please keep us up to date on poor Morgan and how she is doing with her LSL nightmare. I hope the infection clears up soon for her. Best, TbF

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August 12, 2009
Thank you. I will keep you informed about Morgan. All we know right now that it is a raging infection and she will be on IV antibiotics in the hospital for at least one wee, maybe more. It really is very sad and bad. Best, Chrystal Eckes