Can I take Spironolactone while I am on the Depo birth control shot?

Question

I believe I have very hormonal acne, and I have tried many topical creams, and nothing has worked. I think that I need to try taking something that will work from the inside out, as I have had acne that is deep under my skin that topicals can't reach. My dermatologist told me I can try Spironolactone, but I am not sure if it will be ok to take while I am on the Depo shot. I am 23 years old and have been struggling with acne on and off for the last three or so years.

Anna Chacon, MD, FAAD · Answer

Spironolactone is a medication often used off-label to treat hormonal acne. It's generally considered safe to take alongside hormonal birth control, like the Depo-Provera shot. However, as with any medication, there can be potential side effects or interactions, so it's important to discuss this with your healthcare provider.
Your dermatologist would be the best person to provide you with personalized advice based on your medical history and current medications. It's also recommended to consult your gynecologist or the healthcare provider who prescribed your Depo shot to ensure they are aware of any new medications you're considering.

Can I take Spironolactone while I am on the Depo birth control shot?

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