Is Isotretinoin a good option for treating enlarged sebaceous glands? (photo)

Question

I am seeking your advice on whether a low dose of isotretinoin could be effective in treating enlarged sebaceous glands. I have three raised lesions on my nose, initially believed to be scars but recently diagnosed as enlarged sebaceous glands by a dermatologist. Despite undergoing three treatments with Dioxium laser (10600 nm ablative and 1540 nm non-ablative), the issue persists. When I suggested isotretinoin, the doctor mentioned it would only reduce oil production, not shrink the glands.

Anil R. Shah, MD · Answer

Hello! My name is Jessica, I am a physician assistant, and one of the providers at Aesthetic Skin in Winnetka and Chicago. This is a great question. Isotretinoin, commonly known by its brand name Accutane, is indeed an effective option for treating enlarged sebaceous glands, particularly when they are associated with severe acne. This powerful oral medication works by reducing the size and activity of sebaceous glands, leading to a significant decrease in oil production. By shrinking these glands and decreasing sebum production, isotretinoin helps to prevent clogged pores and reduces the incidence of acne. It is especially beneficial for individuals with persistent acne that hasn't responded well to other treatments. However, due to its potent effects and potential side effects, isotretinoin should be prescribed and monitored by a dermatologist. It is important to have a thorough evaluation and discussion with your healthcare provider to weigh the benefits and risks and to determine if isotretinoin is the most appropriate treatment for your specific condition. I hope this helps and best of luck!

Anna Chacon, MD, FAAD · Answer

Isotretinoin can be a useful option for treating enlarged sebaceous glands, but its effectiveness may vary depending on the individual case. Isotretinoin works by significantly reducing the size and activity of sebaceous glands, which can help in reducing oil production and potentially minimizing the appearance of enlarged glands. However, it's important to note that while isotretinoin can reduce the size of sebaceous glands, it may not completely eliminate already enlarged glands.

Given that you have already tried laser treatments without satisfactory results, a low dose of isotretinoin might be worth considering. It’s crucial to have a thorough discussion with your dermatologist about the potential benefits and risks of isotretinoin in your specific situation. They can provide personalized advice and monitor you closely during the treatment.

Please remember that isotretinoin is a potent medication with significant side effects, and its use should be carefully evaluated and supervised by a healthcare professional.

Is Isotretinoin a good option for treating enlarged sebaceous glands? (photo)

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