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Hello, the short answer is yes. Retin-A (generic name tretinoin) and Differin, as well as Tazorac, are topical retinoid creams. They are usually applied as a pea-sized amount at night. If you are alternating between two retinoid creams and using one per night, that should help improve acne and wrinkles. Your skin may peel or feel dry for 4-6 weeks and it often takes 8-12 weeks to see good results.
I have had patients use those medications exactly as you have prescribed and it worked for them.