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Can finasteride/propecia cause lipodystrophy?

james9127Feb 10, 2019
I took finasteride for hair loss for two weeks. I noticed loss of erection strength and then some face bloating which my doctor thought was a localized release of histamine and not really sure if it was related to the drug. I stopped taking it after 14 days, the localized histamine reaction has finally subsided but my face seems noticeably thinner and loss of definition. I have loss some fat mass between cureent and before pictures but not alot 3-5lbs maybe.

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Jeff Rapaport, MD profile photo
Dr. Jeff Rapaport, MD
Dermatologic Surgeon, Board Certified in Dermatology
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Answered on Feb 11, 2019
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Dr. William Rassman, MD (retired)
Hair Restoration Surgeon, Board Certified in General Surgery
Answered on Feb 11, 2019
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Jeff Donovan, MD, PhD

Antiandrogens are compounds that block or inhibit the ability of androgens to do their job in the body. Finasteride is most certainly an anti-androgen.  It lowers levels in the blood and scalp of an androgen known as dihydrotestosterone or DHT. There are many classes of anti-androgens- inc...

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Jeff Donovan, MD, PhD

The full answer to your question is much more involved than the short answer. If having another child is important then a full evaluation of both the male and female partner is important here. For my male patients who say to me “we really want a second child”... getting a sperm count at this jun...

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William Rassman, MD (retired)

We know that when people take DHEA, they lose hair so I am not surprised at your report. Getting it under control in a 'gray' area that I don't understand.

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