Does applying a serum over Tretinoin make it less effective?

Applying a serum or cream after Tretinoin should not necessarily make it less effective, but there are a few considerations to keep in mind:

Absorption Time: It's important to allow Tretinoin sufficient time to absorb into the skin before applying other products. Waiting 20-30 minutes after applying Tretinoin can help ensure it has penetrated the skin effectively.

Product Compatibility: While many serums and creams can be used after Tretinoin, some ingredients might interact or irritate the skin. It's generally recommended to avoid products with strong acids or ingredients that can cause irritation when combined with Tretinoin.

Layering Order: Typically, Tretinoin should be applied directly to clean, dry skin. If applying a serum afterward, ensure it's compatible and non-irritating. Moisturizers can be applied to help with dryness and enhance comfort.

Hydration: Applying a moisturizer after Tretinoin can help seal in moisture and reduce potential dryness or irritation, which is beneficial for maintaining the skin barrier.

Since you haven't experienced side effects with your current routine, it's likely working well for your skin. However, if you introduce a new serum or cream, monitor your skin's response and adjust as needed. Consulting with a dermatologist for personalized advice can also help optimize your skincare regimen.