Is using Epiduo more effective than Adapalene 0.1% + Benzoyl Peroxide 2.5% seperatly ? Retinols not working on my nose (photo)

Question

Hello ! Everything is in the title. I'm asking this question because in France, Epiduo is very very expensive and on the other hand, Adapalene and Benzoyl Peroxyde are two cheap products when single. Second question : Why is retinol working everywhere on my face except on my nose ? I'm using alternately tretinoin 0.05% / adapalene 0.1% with a good skincare routine for almost two years now and my acne on my nose didn't get any better (frequent red bumps, lots of blackheads, redness...).

Anna Chacon, MD, FAAD · Answer

When considering the effectiveness of Epiduo versus using Adapalene 0.1% and Benzoyl Peroxide 2.5% separately, there are a few factors to consider:

Efficacy of Epiduo vs. Separate Use:

Epiduo: This is a combination gel that contains Adapalene 0.1% and Benzoyl Peroxide 2.5% together. The formulation is designed to be stable and effective, benefiting from the synergistic effects of both active ingredients. This combination can enhance the penetration and efficacy of the ingredients.
Separate Use: Using Adapalene and Benzoyl Peroxide separately can be effective as well, particularly if applied correctly as part of a consistent routine. The main advantage of using them together in a product like Epiduo is the convenience and potentially enhanced efficacy due to the formulation.
Cost Considerations: If Epiduo is significantly more expensive, and you find that using the separate products provides similar results when applied in combination, it may be more economical to continue using them separately.

Retinol Effectiveness on the Nose:

Resistance on the Nose: The skin on the nose can be more resistant to treatments due to its thicker texture and the presence of more sebaceous (oil-producing) glands, making it more prone to blackheads and persistent acne.
Treatment Adjustments: Consider treatments specifically targeting blackheads and oiliness, such as salicylic acid or exfoliating acids, which can help with clogged pores. Additionally, ensuring that your skincare routine includes adequate hydration and gentle exfoliation can support the effectiveness of retinoids.
Consultation with a Dermatologist: If you continue to see persistent issues with acne on your nose, consulting a dermatologist may provide more tailored advice. They might suggest alternative treatments like chemical peels, extraction procedures, or other topical medications.

In summary, while Epiduo may offer the convenience of a combined formulation, using Adapalene and Benzoyl Peroxide separately can also be effective if managed properly. Addressing the specific issues on your nose may require additional or alternative treatments tailored to the unique characteristics of that area.

Is using Epiduo more effective than Adapalene 0.1% + Benzoyl Peroxide 2.5% seperatly ? Retinols not working on my nose (photo)

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