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Can I start taking Minocycline along with spironolactone?

rilynntMay 17, 2018
I have been taking Spironolactone 150mg for 2 months now. the first month I had a horrible initial breakout, and now it has gotten a little better but still breaking out. I know spironolactone can take 3-4 months to really start working, so I was wondering if I could begin taking minocycline to help until the spiro really kicks in. I have taken minocycline in the past and it works really well for me.

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From board-certified doctors and trusted medical professionals
Dr. Sarah B. Sawyer, MD
Board Certified Dermatologist
Answered on Jul 18, 2018
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Laura A. Katz, MD

Spironolactone and trinessa do not have any specific interactions with each other.  However, spironolactone can cause menstrual irregularities. Triphasic birth control pills such as your trinessa can also sometimes cause menstrual irregularities on their own, altho it sounds like your issue...

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Laura A. Katz, MD

As far as spironolactone side effects, it can cause its own menstrual irregularities esp when you first use it. Since it is originally a diuretic blood pressure agent, you have to monitor potassium. Weight gain shouldnt really be an issue since you tend to urinate more fluids when you are on...

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Reuel Aspacio, MD, FAAD - Account Suspended

Thank you for your question. It is common to have breakouts when starting any acne treatment, and in my experience, breakouts may last weeks to months before acne improves and clears. If acne breakouts are severe, there are additional treatments that can help, so I highly recommend you consult...

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