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Thanks for your question. Adapalene is a synthetic retinoid, and is the weakest of all the prescription strength products, although it went over the counter a number of years ago. It tends to be more well-tolerated and less drying than tretinoin. Prescription Tretinoin, or generic Retin-a, comes in three strengths for the most part: 0.025%, 0.05%, and 0.1%. 0.1% is the strongest and would work the best for anti-aging, but all the retinoids have a role in helping with skin texture, reducing fine lines and wrinkles, helping to gradually lift pigment, and strengthening the skin. Whatever you tolerate and are willing to use, you will see some benefit from any of these products. See a dermatologist for a skin exam at some point and they will also be able to help you decide which retinoid would be best for your age and skin type. Take care!