What is the difference between having Radiesse vs Restylane filler for nasolabial folds? Which is better?

In my experience, all three of these products work beautifully for the nasolabial folds, also called the parentheses lines, extending between the edges of the nostrils and the corners of the mouth. The primary difference between them is that Restylane and Juvederm are have a shorter duration (~ 6-9 months) as compared with Radiesse, which can last up to 18 months or longer. I have not found a difference in duration between Restylane and Juvederm. The advantage of these hyaluronic acid (HA) fillers is that they can be dissolved with a simple injection of hyaluronidase in the unlikely event of a lump or asymmetry. Radiesse cannot be dissolved and is slightly more expensive at our center. I have not found a difference in the degree of bruising with any of these fillers. 

The volume line on nasolabial folds can be restored with the injection of fillers. There is no filler better than the other. The discussion of using Radiesse vs Restylane or Juvederm, will depend on the severity of the volume line. For this area there has been great advances and my preference is to inject Restylane Defyne or Refyne since the way they were engineered makes them more flexible which contribute to their natural look.

Hello,
Good question as both are good options.  However,we often are determining which is the best product for a patient if both are considered equally good.  This decision is based upon patient's age, condition, skin turgor, bone structure, and degree of need for correction.  For example, a patient that is over 40 with heavy laugh lines from aging  may do better with Radiesse for it's lifting/support quality.  Restylane LYFT does this as well, but we find Radiesse has a better "tug and hold" ability.  For a younger patient that only requires a mild correction, Restylane or Restylane LYFT may be appropriate.  
Referring back to your question as to durability and duration - we believe the most important factor is having enough product to reach your goals.  Oftentimes, a patient will not achieve their goals because their budget did not allow for full correction.  Be certain to discuss this with your injector so that your options are understood.

Restylane and Juvederm are both hyaluronic acid gel fillers that can provide immediate volume to the nasolabial folds, and are both commonly used for this purpose. Radiesse is a different type of filler that actually stimulates the body’s own collagen production using calcium hydroxylapatite microspheres. Radiesse is longer lasting in the nasolabial folds, but Juvederm or Restylane may be appropriate as well depending on the severity of your fold.. I would visit a board-certified dermatologist to discuss your goals and decide on the best treatment plan. 

Juvederm, restylane and radiesse are all great fillers for the nasolabial folds.  More importantly than the product, however, is the qualifications of the injector. There are more advance techniques that can be used to soften the nasolabial fold asides from directly filling them.  Also you have other options such as Sculptra or fat grafting that can also provide a nice softening of this area.

Radiesse is a calcium based product in a gel that lifts and restores volume.  Often, the nasolabial folds are secondary to flat cheeks. The cheeks hold up the face, so when there is no support the skin sags.  First ,I fill the cheeks with Radiesse.  Radiesse can also be placed in the upper nasolabial fold next to the nose.  The remainder of the fold, if it still is very visible, can then be softened with Restylane, a hyaluronic acid product.  I prefer Juvederm for this area.  The art is knowing where each product works best and injecting it in a manner that produces a natural and rejuvenated appearance.