Radeisse Vs. Sculptra for Marionette Lines

As previously mentioned, Radiesse provides more initial capacity to fill lines and wrinkles and Sculptra is a delayed, collagen inducing volumizing agent.  The technique with Scupltra has moved more toward deeper injections in order to compensate for loss of deeper facial fat that occurs over time.  Radiesse is typically injected more superficially in the sub-dermis.  Both agents can be beneficial in this area, but the results are much slower and gradual with Scupltra.

If you're describing the marionette lines, I find that Radiesse, Restylane or Juvederm are more practical than Sculptra as the former can be placed directly in the intended area and Sculptra is more of a seed that stimulates your body's production of collagen. It is great when the area for volumization is more broad than a fine line. 

Radiesse gives immediate results and is more economical than Sculptra. While Sculptra might last 6 months longer than Radiesse (18-24 months vs. 12-18 months) it needs several treatments before you see results, which can take months.