Can Prednisone Affect Sculptra?

Question

I had to have a short 5 day low dose course of Prednisone to deal with poison ivy. I had sculptra almost three months ago and had already seen filling occuring. Now just two days after the Prednisone, my face literally looks deflated. Is that possible? It was working so well.

Ron Shelton, MD · Answer

Sculptra helps your body produce collagen.  That is similar to the process of inflammation and for the several days you took the Prednisone, there may be less inflammation.  There may be less production of collagen by the fibroblast cells that make the collagen during this time, but the prednisone doesn't kill those cells, just inhibit them. Sculptra is a long term process and a week of reduction of its collagen stimulation, if that occurs from prednisone, should not prevent its ongoing effect.

William Ting, MD · Answer

While a prolonged course of prednisone immediately after Sculptra injection may potentially hamper optimal stimulation of collagen by Sculptra, it is unlikely that a low-dosed short course of prednisone 3 months after last Sculptra injection would have any significant impact.

Jo Herzog, MD · Answer

The short course of steroids that you have taken, well after the sculptra has done most of it's work, should not be any problem. This probably all represented changes in fluid retention during steroid use and loss of that after.

Madeline Krauss, MD · Answer

By 3 months post your Sculptra treatment, you have had most of your collagen deposition completed from your treatment.  I would be more concerned if you had the prednisone within the first 4 weeks.   Also 5 days is a relatively short time, whereas a longer course might have more effect on collagen deposition.

Arnold W. Klein, MD (in memoriam) · Answer

Sculptra works by causing a immune reaction to the product.  This is the last thing you want a filler to do.In certain studies up to 50% of individuals injected developed lumps. So Prednisone stopped the Allergic reaction and also the affect of the agent.

Can Prednisone Affect Sculptra?

Answers (8)

Answer: Prednisone and Sculptra

Answer: Prednisone and Sculptra

Answer: Prednisone stopped the reaction to Sculptra

Answer: Prednisone stopped the reaction to Sculptra

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Can Prednisone Affect Sculptra?

Answers (8)

Answer: Prednisone and Sculptra

Answer: Prednisone and Sculptra

Answer: Prednisone stopped the reaction to Sculptra

Answer: Prednisone stopped the reaction to Sculptra

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Recommended reading

Everything you need to know about Sculptra

Our mission is to create a world where every investment in modern beauty is Worth It.