It's important to follow your doctor's advice, but it's also understandable to have concerns about how medications might interact with your treatments. Here are a few points to consider: 1. **Role of Prednisolone**: Prednisolone is a corticosteroid that reduces inflammation and suppresses the immune system. It can be prescribed for various reasons, including managing inflammation, allergic reactions, and certain skin conditions. 2. **Dermapen and Inflammation**: Dermapen (microneedling) treatments create controlled micro-injuries to the skin, which can stimulate collagen production and promote healing. Some inflammation is a natural part of this healing process, and it can be beneficial for skin rejuvenation. 3. **Effect of Anti-Inflammatories**: There is some debate about whether using anti-inflammatory medications like prednisolone after microneedling might interfere with the desired inflammatory response. However, this largely depends on the specific indications and the doctor's rationale for prescribing the medication. 4. **Active Acne**: If you have active acne, your doctor might have prescribed prednisolone to help reduce inflammation and prevent further breakouts. Acne can complicate the healing process and potentially lead to more severe skin issues if not managed properly. **Recommendations**: - **Consult Your Doctor**: The best course of action is to discuss your concerns directly with the prescribing physician. They can provide you with a detailed explanation tailored to your specific condition and treatment plan. - **Follow Professional Guidance**: Your doctor has considered your overall health, skin condition, and the benefits versus risks of using prednisolone in your case. It's essential to follow their advice unless you have a clear reason to believe otherwise. - **Monitor Your Skin**: Keep an eye on how your skin responds to the treatment and medication. If you notice any adverse reactions or if your skin condition worsens, contact your doctor immediately. If you need more information or have specific concerns, don't hesitate to reach out to your healthcare provider for personalized advice.