PMMA Injections for Buttock Augmentation Side Effects?

I have done some research on PMMA (Polymethylmethacrylate) injections and I found all the benefits however, I have not been able to find the side effects. If you are aware of any useful, reliable websites for information please share them with me.

Doctor Answers 4

PMMA Injections for Buttock Augmentation Side Effects?

PMMA is a permanent material.  Once it is injected it is impossible to completely remove.  The BIG problem with these types of injections is that the body reacts by forming scar tissue around the material injected.  This can lead to such complications as contour deformities, hardening of normally soft tissues, intractable pain, and infections that never resolve.  I can tell you from my own experience treating multiple unfortunate patients with PMMA injections that these complications do occur and are difficult or impossible to correct.  Stay safe and avoid these illegal products!  

Houston Plastic Surgeon
4.0 out of 5 stars 11 reviews

PMMA for buttocks is too expensive and not approved

PMMA comes in very small quantities, about one cc per syrige. You need about 300-500cc per buttock, that becomes too expensive.

PMMA is not approved for butt enhancement.

Fat Transfer is much better, if you have enough fat to transfer.

Samir Shureih, MD
Baltimore Plastic Surgeon
4.2 out of 5 stars 7 reviews

PMMA for buttock augmentation

Artefill is a PMMA containing filler that is FDA approved for correction of the Nasolabial folds. Although originally manufactured by Artes Medical (reportedly bankrupt), it has been picked up by Suneva for distribution.

It is 80% Bovine (cow) Collagen and 20% PMMA. Each 1cc syringe when administered by a physician may range from $1000-2000. If you consider that the average buttock augmentation typically requires a minimum of 250cc (multiplied by 2 for two sides = 500cc). Do the math and you can see that this would be cost prohibitive.

Clearly this is available for use as an off-label indication. However the economic costs are not the reason why physicians do perform the procedure. There are concerns with granuloma formation and other possible side effects.

Otto Joseph Placik, MD
Chicago Plastic Surgeon
4.9 out of 5 stars 82 reviews

PMMA injections for Buttock Augmentation


PMMA injections are NOT approved by the FDA for soft tissue augmentation. No REPUTABLE Plastic surgeon will do them because it involves placing small, hard particles in soft tissue which leads to irreversible scarring and life long complications. DO NOT DO IT.

Peter A. Aldea, MD
Memphis Plastic Surgeon
4.9 out of 5 stars 109 reviews

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.