Does Photodynamic Therapy Permanently Minimize the Sebaceous Glands?

Levulan is absorbed preferentially in sebaceous glands.  After laser or light activation, there is "shrinkage" of these glands and therefore improvement in patients with acne.  After 2 or 3 treatments, there is long term control of acne (some have 5 years or more).  However, more commonly, yearly treatments are needed to control the acne because the sebaceous glands gradually grow back.  

A published medical article demonstrated that sebaceous hyperplasia (enlarged oil glands) respond favorably to a series of PDT treatments.  However, PDT will not permanently reverse your likelihood to develop new lesions.  Maintenance PDT therapy or other destructive treatment options may be necessary from time to time to keep your skin clear of enlarged oil glands.

PDT can be ab effective treatment for enlarged sebaceous glands, enlarged pores, and acne. ALA application followed by blue light may be necessary for best results.