Hi, thanks for the question!Officially, the Orbera balloon can be filled with anywhere between 400ml and 700ml of saline. In the pivotal US clinical study, the balloon was filled with between 500ml and 600ml of saline, which is what most providers will use. I typically recommend 600ml for all patients, unless you are shorter (say, less than 5 feet 2 inches), in which case a smaller volume may be better tolerated. Interestingly, you might think that a larger fill volume would lead to more weight loss, but it actually doesn't. A review of 80 studies (including 8,506 patients) showed that there was no relationship between fill volume (including up to 700ml) and total weight loss.
