What happens if you go on and off propecia over time?

Question

I started on Propecia 2 years ago and got good results. After a year I forgot my pills on a trip and was 14 days without. Then I got back on. Then I started taking pills every 3 days as I read a study that it would be enough. After this I have been inconcistantly using it and I see it has no effect as the hair has gone thinner. Would it be benefitial to start on it a 100% again?

Roy Stoller, DO, FAOCO, FAAO · Answer

Propecia works by lowering DHT (dihydrotestosterone) levels. This hormone is the culprit that in thinning and eventual hair loss seen in male pattern baldness.  Since hair cycles between a rest and active phase, Propecia will effect cycling time.  When hair is in the rest phase, telogen, hair is asleep and not growing.  I have seen patients cause a longer than usual sleep phase which results in shedding.  Patients need to make a commitment when starting Propecia to stay on it unless side effects ensue.  You could be less responsive to Propecia than before or the thinning you are experiencing could be secondary to increased shedding.  It would be a good idea for you to follow up with your physician.

Jeff Donovan, MD, PhD · Answer

Studies of what happens when people go on and off have never been done. However, it's clear in my mind that men who cycle on and off tend to respond poorly over time. If started a constant dose is advised. Please see your hair loss physician to review dosing and frequency.

William Rassman, MD (retired) · Answer

Genetic loss can get to the point where it is not reversible. Finasteride, if used, must be consistent. When you goi off of if, then you may lose hair permanently

What happens if you go on and off propecia over time?

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What happens if you go on and off propecia over time?

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