I had sinus surgery 2 years ago and ended up with a pretty nasty infection that took about 5 months to get rid of. I was put on Cipro, bactrum, and few other antibiotics that I can't think of off the top of my head. Do I have a higher risk of getting another infection in the future?
April 6, 2011
Answer: Infection after sinus surgery
Sandy, As you know MRSA infections, which used to be mostly confined to institutions such as hospitals and nursing homes, are increasingly occuring in the community in otherwise healthy people. Therefore it is difficult to know if your postoperative infection was from the place where you had your sinus surgery or it was acquired within your community. These infections can be difficult to eradicate because the organism is often resistant to multiple other antibiotics, not just methicillin and its derivatives. Nebulized vancomycin can be very effective.
However staphylococcus is notorious for forming biofilms which are bacterial colonies within a gel-like substance. The bacteria stop reproducing but still can elaborate toxins that can damage the sinus linings causing them to lose cilia, the microscopic fingers that move mucous out of the sinuses. Since antibiotics only kill dividing bacteria the organisms within the biofilm continue to survive. That being said you might be more likely to have other infections based upon the continued presence of biofilms and the degree of permanent mucous membrane injury. Some have advocated a dilute nasal irrigation solution of baby shampoo as the detergent action of the shampoo helps to break up the biofilm so that bacteria start reproducing again making them susceptible to destruction by antibiotics. A long-winded answer to your question but I hope that helps. Should MRSA recur try vancomycin nebs.
Helpful 2 people found this helpful
April 6, 2011
Answer: Infection after sinus surgery
Sandy, As you know MRSA infections, which used to be mostly confined to institutions such as hospitals and nursing homes, are increasingly occuring in the community in otherwise healthy people. Therefore it is difficult to know if your postoperative infection was from the place where you had your sinus surgery or it was acquired within your community. These infections can be difficult to eradicate because the organism is often resistant to multiple other antibiotics, not just methicillin and its derivatives. Nebulized vancomycin can be very effective.
However staphylococcus is notorious for forming biofilms which are bacterial colonies within a gel-like substance. The bacteria stop reproducing but still can elaborate toxins that can damage the sinus linings causing them to lose cilia, the microscopic fingers that move mucous out of the sinuses. Since antibiotics only kill dividing bacteria the organisms within the biofilm continue to survive. That being said you might be more likely to have other infections based upon the continued presence of biofilms and the degree of permanent mucous membrane injury. Some have advocated a dilute nasal irrigation solution of baby shampoo as the detergent action of the shampoo helps to break up the biofilm so that bacteria start reproducing again making them susceptible to destruction by antibiotics. A long-winded answer to your question but I hope that helps. Should MRSA recur try vancomycin nebs.
Helpful 2 people found this helpful