Microdermabrasion would be a poor choice to rid yourself of sebaceous hyperplasia. Incidentally, this is one condition that seems to worsen with age. I remember picking up this tidbit during medical school. There are supposedly two glands which enlarge as you get older: the prostate gland and the sebaceous gland. Anyway, microdermabrasion will do little, if anything, for sebaceous gland hyperplasia. There are a variety of treatments available. I like 85% trichloracetic acid. The acid dissolves the fatty sebaceous gland, but the collagen of the dermis is resistant. It is a good, relatively painless, inexpensive choice. Also, buzzing them with a bit of low current electrocautery will make them dissolve. If you have other skin issues, then photodynamic therapy may help. Donald Richey wrote about this in Dermatology Clinics (2007) and Tina Alster described this method a few years before that. If you have some recalcitrant acne with these lesions, a five month course of Accutane will bet rid of these troublesome growths permanently. This treatment is overkill for sebaceous gland hyperplasia by itself.