Can tear trough fillers be applied days after Plinest/Rejuran?

When considering the timing of aesthetic treatments like Plinest (a polynucleotide-based skin booster) and tear trough fillers, it’s crucial to ensure that the skin has adequately recovered from the first procedure before undergoing another. This helps to minimize the risk of complications, such as inflammation, bruising, or adverse reactions.

Plinest and Rejuran are polynucleotide treatments designed to improve skin quality, hydration, and overall appearance by stimulating collagen production and providing other regenerative benefits. These treatments typically involve multiple tiny injections into the skin.

Here are some points to consider regarding the timing of your treatments:

1. **Healing Time**: After a Plinest treatment, the skin may need some time to recover from the micro-injections. This recovery period can vary from person to person but typically lasts a few days to a week.

2. **Inflammation and Swelling**: Both Plinest and tear trough fillers can cause some degree of inflammation and swelling. Having the treatments too close together may exacerbate these effects and make it difficult to assess the filler placement accurately.

3. **Risk of Infection**: Multiple procedures in a short period can increase the risk of infection. It is generally advised to allow the skin to fully heal from one treatment before proceeding with another.

4. **Optimal Results**: For the best aesthetic results, it might be beneficial to allow the full effect of the Plinest treatment to manifest before adding dermal fillers. This can help in better assessing the areas that need additional volume or correction.

Given these considerations, it is generally advisable to wait at least one to two weeks between these types of treatments. However, individual factors such as your skin's healing response, the extent of the initial treatment, and your overall health can influence this timing.

**Recommendation**:
Consult with your treating physician or a qualified aesthetic practitioner who can assess your specific situation. They can provide personalized advice based on the condition of your skin and the details of your treatments. If there is any uncertainty or if you experience any adverse reactions from the Plinest treatment, it may be wise to postpone the tear through fillers until your skin has fully recovered.

Both Plinest/Rejuran are polynucleotide injectable collagen biostimulators that stimulate your skin in a non-inflammatory process.However, in my practices, I usually recommend my patients not to have any injection procedures at least 2 weeks before dermal filler injection, especially in the same area of treatment. The reason is that with any kind of injection, you can have some unusual reaction or tissue inflammation. Dermal filler injection needs an accurate evaluation to decide the proper type and amount of the filler to be injected.