I have been using the Fraxel RE:restore for 5 years and have treated pigmentation of the face, neck, declotte, hands/arms, and shoulders with great success. If the patients follow our instructions regarding suntanning and use of UVA/UVB sunblock with an SPF of 30+, their results can last years. This is also very dependent on the area of the US you live. My practice is in Tampa, Forida and the sun is very strong and watersports prevail. Therefore, my patients understand the need to re-apply constantly. I have also treated post acne scars and traumatic scars with the RE:store with great results. Severe stretch marks may respond better to the RE:pair.