Anjali Butani, MD says:Tretinoin generally comes in 0.025%, 0.05% and 0.1%. Retin-A comes in 0.04% and 0.1%. As these are prescribed medications, your dermatologist should decide which strength is best for you. In general, if you have dry, sensitive skin, start low (0.025% or 0.04%). You can always go stronger...