Mesotherapy/injection lipolysis is not FDA approved in the US and is not regulated. Results are reported to be variable and unpredictable. Injections are painful as is the aftermath (swelling and inflammation). It is not to say that with more study, quality control and refinement that it could not be a good procedure. On the other hand Liposonix is FDA approved, has a great track record in Canada and elsewhere in the world and is safe and effective. I would definitely go with Liposonix.
As of Dec. 2011, I'm one of the first U.S. centers to offer the Liposonix, the first FDA approved fat melting device (approved Nov 2011 for fat reduction of the abdomen and flanks--it can be used off-label to treat other body parts). It uses high-intensity focused ultrasound (HIFU) to cause lysis or destruction of the fat cells. There is no other device that can make this claim in the U.S. It is nonsurgical liposuction, a revolutionary technologic breakthrough. It is not a replacement for liposuction because you cannot remove the high volumes of fat possible thru liposuction but you can get about an inch reduction (2.5 cm) in fat per treatment per area. UltraShape also uses HIFU but has not received FDA clearance and is not available in the U.S. Clinical trials for both devices have shown impressive and consistent results. Injection lipolysis (ie: phosphatidylcholine, succinyl cholate, Lipodissolve) also known as mesotherapy is not standardized nor FDA approved in the U.S. The amount of fat claimed to be dissolved with these chemicals has been inconsistent and to much lesser degree compared to the HIFU devices.
