Is Latisse Safe for Someone Who Has Sjorgren's Syndrome?

You need to ask your personnal doctor but, i doubt that increased dryness will ocur Also, seek an opthamolgical consultation. be sure to use it properly. Get lessons on how to apply

The major "ingredient" of Latisse is latanoprost.  This is a pro-inflammatory medication. Sjogrens is essentially an autoimmune condition and so it could worsen your dry eyes if the medication gets in your eyes. If you apply it strictly to your upper lashes you should be ok. I would wait on trying it until your Sjogrens is well controlled first. 

Sjorgren's Syndrome is usually marked with dryness of the eyes and mouth, as well as other complications. With the proper application of Latisse, none should get in the eye and it should have no effect on eye dryness. However, since you already have issues with your eyes, you need to consult your physician to determine his or her stance on your using Latisse. Even though the two should not affect each other, you need to be safe and protect your eyes as much as possible.